Pyrrole is a versatile heterocyclic moiety exhibiting a wide range of pharmacological actions
with high therapeutic value. The importance of pyrrole in the pharmaceutical field lies in its …

The geometrical structure of t‑butyl‑3, 4, 5-trimethyl-2-pyrrole carboxylate (TBTPC) was
computed by DFT calculations using the B3LYP method and the 6–311++ G (d, p) basis set …

Pyrrole derivatives are known as building blocks for the synthesis of biological compounds
and pharmaceutical drugs. Several processes were employed to synthesize pyrroles …

Background: Bioconjugates are promising alternatives for the multiple targeting of any
disease. Pyrrole heterocycle is well known with many activities and is a building block of a …

Structurally diverse pyrroles were synthesized by direct coupling of α, β‐unsaturated
aldehydes and phenacyl azides. The scope of the synthetic method was successfully …

Parkinson's disease is a huge burden in modern medicinal practice. A serious drawback of
current antiparkinsonian therapy is its symptomatic nature. This directed our investigations in …

Background Neuroinflammation and oxidative stress are critical factors involved in the
pathogenesis of Parkinson's disease (PD), the second most common progressive …