Recent Progress for the Synthesis of Pyrrole Derivatives–An Update
Pyrrole is a versatile heterocyclic moiety exhibiting a wide range of pharmacological actions
with high therapeutic value. The importance of pyrrole in the pharmaceutical field lies in its …
with high therapeutic value. The importance of pyrrole in the pharmaceutical field lies in its …
Spectroscopic investigations, quantum chemical, molecular docking and drug likeness studies of t-butyl-3, 4, 5-trimethyl-2-pyrrole carboxylate
AK Bharathi, SC Jeyaseelan, S Hussain… - Journal of Molecular …, 2024 - Elsevier
The geometrical structure of t‑butyl‑3, 4, 5-trimethyl-2-pyrrole carboxylate (TBTPC) was
computed by DFT calculations using the B3LYP method and the 6–311++ G (d, p) basis set …
computed by DFT calculations using the B3LYP method and the 6–311++ G (d, p) basis set …
Green Synthesis of Bioactive Pyrrole Derivatives via Heterogeneous Catalysts Since 2010
B Amina, B Redouane - Current Topics in Medicinal Chemistry, 2024 - ingentaconnect.com
Pyrrole derivatives are known as building blocks for the synthesis of biological compounds
and pharmaceutical drugs. Several processes were employed to synthesize pyrroles …
and pharmaceutical drugs. Several processes were employed to synthesize pyrroles …
[HTML][HTML] Synthesis, Hydrolytic Stability and In Vivo Biological Study of Bioconjugates of the Tetrapeptides FELL Containing Pyrrole Moiety
B Borisova, S Vladimirova, H Nocheva… - Biomedicines, 2023 - mdpi.com
Background: Bioconjugates are promising alternatives for the multiple targeting of any
disease. Pyrrole heterocycle is well known with many activities and is a building block of a …
disease. Pyrrole heterocycle is well known with many activities and is a building block of a …
Practical Synthesis of Pharmaceutically Relevant Pyrroles from α,β‐Unsaturated Aldehydes and Phenacyl Azides
L Borkotoky, RA Maurya - European Journal of Organic …, 2023 - Wiley Online Library
Structurally diverse pyrroles were synthesized by direct coupling of α, β‐unsaturated
aldehydes and phenacyl azides. The scope of the synthetic method was successfully …
aldehydes and phenacyl azides. The scope of the synthetic method was successfully …
[HTML][HTML] In silico evaluation and in vitro determination of neuroprotective and MAO-B inhibitory effects of pyrrole-based hydrazones: A therapeutic approach to …
M Kondeva-Burdina, E Mateev, B Angelov, V Tzankova… - Molecules, 2022 - mdpi.com
Parkinson's disease is a huge burden in modern medicinal practice. A serious drawback of
current antiparkinsonian therapy is its symptomatic nature. This directed our investigations in …
current antiparkinsonian therapy is its symptomatic nature. This directed our investigations in …
[HTML][HTML] Biological Activity of Novel Pyrrole Derivatives as Antioxidant Agents Against 6-OHDA Induced Neurotoxicity in PC12 Cells
H Javid, ES Moghadam, M Farahmandfar… - Iranian journal of …, 2023 - ncbi.nlm.nih.gov
Background Neuroinflammation and oxidative stress are critical factors involved in the
pathogenesis of Parkinson's disease (PD), the second most common progressive …
pathogenesis of Parkinson's disease (PD), the second most common progressive …