Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Nucleic acid detection using CRISPR/Cas biosensing technologies

R Aman, A Mahas, M Mahfouz - ACS synthetic biology, 2020 - ACS Publications
For infectious diseases, rapid and accurate identification of the pathogen is critical for
effective management and treatment, but diagnosis remains challenging, particularly in …

Advances in chemical and biological methods to identify microorganisms—from past to present

R Franco-Duarte, L Černáková, S Kadam, K S. Kaushik… - Microorganisms, 2019 - mdpi.com
Fast detection and identification of microorganisms is a challenging and significant feature
from industry to medicine. Standard approaches are known to be very time-consuming and …

Diagnosis of invasive fungal infections: challenges and recent developments

W Fang, J Wu, M Cheng, X Zhu, M Du, C Chen… - Journal of biomedical …, 2023 - Springer
Background The global burden of invasive fungal infections (IFIs) has shown an upsurge in
recent years due to the higher load of immunocompromised patients suffering from various …

Neuroinfections caused by fungi

K Góralska, J Blaszkowska, M Dzikowiec - Infection, 2018 - Springer
Background Fungal infections of the central nervous system (FIs-CNS) have become
significantly more common over the past 2 decades. Invasion of the CNS largely depends on …

T2 magnetic resonance assay for the rapid diagnosis of candidemia in whole blood: a clinical trial

E Mylonakis, CJ Clancy… - Clinical Infectious …, 2015 - academic.oup.com
Background. Microbiologic cultures, the current gold standard diagnostic method for
invasive Candida infections, have low specificity and take up to 2–5 days to grow. We …

Consensus guidelines for the diagnosis and management of invasive aspergillosis, 2021

AP Douglas, OC Smibert, A Bajel… - Internal Medicine …, 2021 - Wiley Online Library
Invasive aspergillosis (IA) in haematology/oncology patients presents as primary infection or
breakthrough infection, which can become refractory to antifungal treatment and has a high …

Diagnosis and treatment of community‐acquired pneumonia in adults: 2016 clinical practice guidelines by the Chinese Thoracic Society, Chinese Medical Association

B Cao, Y Huang, DY She, QJ Cheng… - The clinical …, 2018 - Wiley Online Library
Community‐acquired pneumonia (CAP) in adults is an infectious disease with high
morbidity in China and the rest of the world. With the changing pattern in the etiological …

[HTML][HTML] A new age in molecular diagnostics for invasive fungal disease: are we ready?

SE Kidd, SCA Chen, W Meyer, CL Halliday - Frontiers in microbiology, 2020 - frontiersin.org
Invasive fungal diseases (IFDs) present an increasing global burden in
immunocompromised and other seriously ill populations, including those caused by …

Efficacy of transfusion with granulocytes from G-CSF/dexamethasone–treated donors in neutropenic patients with infection

TH Price, M Boeckh, RW Harrison… - Blood, The Journal …, 2015 - ashpublications.org
High-dose granulocyte transfusion therapy has been available for 20 years, yet its clinical
efficacy has never been conclusively demonstrated. We report here the results of RING …