The blood brain barrier (BBB) is the main barrier that separates the blood from the brain.
Because of the BBB, the drug concentration-time profile in the brain may be substantially …

One of the obstacles limiting progress in the development of effective cancer therapies is the
shortage of preclinical models that capture the dynamic nature of tumor microenvironments …

Atherosclerotic plaques and thrombosis are chronic inflammatory complications and the
main manifestations of cardiovascular diseases (CVD), the leading cause of death globally …

We study the performance of direct solvers on linear systems of equations resulting from
isogeometric analysis. The problem of choice is the canonical Laplace equation in three …

Spheroid‐on‐a‐chip platforms are emerging as promising in vitro models that enable
screening of the efficacy of biologically active ingredients. Generally, the supply of liquids to …

The first book offering a global overview of fundamental microfluidics and the wide range of
possible applications, for example, in chemistry, biology, and biomedical science. As such, it …

Development of many conditions and disorders, such as atherosclerosis and stroke, are
dependent upon hemodynamic forces. To accurately predict and prevent these conditions …

Abstract Purpose of Review Nanoparticles are crucial for developing patient-/target-specific
drug delivery systems. In recent days, mathematical modeling and simulation plays an …

Aims: To predict the deposition of nanoparticles in a patient-specific arterial tree as a
function of the vascular architecture, flow conditions, receptor surface density and …

Abstract Development of in silico models that capture progression of diseases in soft
biological tissues are intrinsic in the validation of the hypothesized cellular and molecular …