Over the past two decades, ketamine has emerged as a novel effective and rapid-acting
antidepressant. While the vast majority of studies on ketamine have focused on its ability to …

Psychiatry has always been characterized by a range of different models of and approaches
to mental disorder, which have sometimes brought progress in clinical practice, but have …

Several evidence-based treatments for posttraumatic stress disorder (PTSD) are
recommended by international guidelines (eg, APA, NICE). While their average effects are in …

There is a largeand growing need for mental health services worldwide, but there is a
massive shortage of mental health specialists to meet these needs—particularly …

Personalization of psychological therapies has always been used by clinicians and
describes all efforts to select, adjust, or modify a treatment for the individual to improve …

Practitioners and researchers alike assume that there is individual variability in the effects of
treatments for mental disorders. However, for psychotherapy, up to now this assumption has …

Developing a more comprehensive understanding of the physiological underpinnings of
mental illness, precision medicine has the potential to revolutionize psychiatric care. With …

A randomized controlled trial (RCT) is used to study the safety and efficacy of new
treatments, by comparing patient outcomes of an intervention group with a control group …

Patient‐reported helpfulness of treatment is an important indicator of quality in patient‐
centered care. We examined its pathways and predictors among respondents to household …

A subgroup of patients with schizophrenia is believed to have aberrant excess of glutamate
in the frontal cortex; this subgroup is thought to show poor response to first-line antipsychotic …