Pancreatic cancer (PC) is a fatal disease that has a poor 5-year survival rate. The poor
prognosis can be attributed to both troublesome detections at the initial stage, which makes …

Aptamers are single-stranded nucleic acid molecules that bind to and inhibit proteins and
are commonly produced by systematic evolution of ligands by exponential enrichment …

Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-
stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar …

Conventional anticancer therapies, such as chemo-and/or radio-therapy are often unable to
completely eradicate cancers due to abnormal tumor microenvironment, as well as …

Breast carcinoma is a molecularly diverse illness, and it is among the most prominent and
often reported malignancies in female across the globe. Surgical intervention …

DNA origami provides rapid access to easily functionalized, nanometer‐sized structures
making it an intriguing platform for the development of defined drug delivery and sensor …

Targeted delivery of anti-cancer agents exclusively to tumor cells introduces an attractive
strategy because it increases the therapeutic index compared with untargeted drugs …

Aptamers are nucleic acids referred to as chemical antibodies as they bind to their specific
targets with high affinity and selectivity. They are selected via an iterative process known as …

Chemotherapeutic agents have been used for the treatment of numerous cancers, but due to
poor selectivity and severe systemic side effects, their clinical application is limited. Single …

Gemcitabine has been considered a first-line chemotherapy agent for the treatment of
pancreatic cancer. However, the initial response rate of gemcitabine is low and …