Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy. PDAC is only
cured by surgical resection in its early stage, but there remains a relatively high possibility of …

Toll-like receptors (TLRs) activation enables host to recognize a large number of pathogen-
associated molecule patterns (PAMPs), ignite immune cells to discriminate between self and …

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related mortality in
the United States and has only recently achieved a 5-yr survival rate of 10%. This dismal …

Cellular energy metabolism not only promotes tumor cell growth and metastasis but also
directs immune cell survival, proliferation and the ability to perform specific and functional …

The toll‐like receptor (TLR) family consists of vital receptors responsible for pattern
recognition in innate immunity, making them the core proteins involved in pathogen …

In the dark path of tumorigenesis, the more carefully the cancer biology is studied, the more
brilliant answers could be given to the countless questions about its orchestrating derivers …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant diseases
worldwide. It is refractory to conventional treatments, and consequently has a documented 5 …

Toll-like receptor 2 (TLR2) expressed on myeloid cells mediates the recognition of harmful
molecules belonging to invading pathogens or host damaged tissues, leading to …

The main cause of cervical cancer is persistent infection with high-risk human papilloma
virus (HR-HPV), but not all human papilloma virus (HPV) infections lead to cervical cancer …

Gut microbiota is key to the development and modulation of the mucosal immune system. It
plays a central role in several physiological functions, in the modulation of inflammatory …