Composition and functions of bacterial membrane vesicles

M Toyofuku, S Schild, M Kaparakis-Liaskos… - Nature Reviews …, 2023 - nature.com
Extracellular vesicles are produced by species across all domains of life, suggesting that
vesiculation represents a fundamental principle of living matter. In Gram-negative bacteria …

[HTML][HTML] Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

C Schwechheimer, MJ Kuehn - Nature reviews microbiology, 2015 - nature.com
Outer-membrane vesicles (OMVs) are spherical buds of the outer membrane filled with
periplasmic content and are commonly produced by Gram-negative bacteria. The production …

Outer membrane vesicles: biogenesis, functions, and issues

R Juodeikis, SR Carding - Microbiology and Molecular Biology …, 2022 - Am Soc Microbiol
This review focuses on nonlytic outer membrane vesicles (OMVs), a subtype of bacterial
extracellular vesicles (BEVs) produced by Gram-negative organisms focusing on the …

Bacterial outer membrane vesicles as potential biological nanomaterials for antibacterial therapy

W Huang, L Meng, Y Chen, Z Dong, Q Peng - Acta biomaterialia, 2022 - Elsevier
Antibiotic therapy is one of the most important approaches against bacterial infections.
However, the improper use of antibiotics and the emergence of drug resistance have …

[HTML][HTML] Contribution of bacterial outer membrane vesicles to innate bacterial defense

AJ Manning, MJ Kuehn - BMC microbiology, 2011 - Springer
Abstract Background Outer membrane vesicles (OMVs) are constitutively produced by Gram-
negative bacteria throughout growth and have proposed roles in virulence, inflammation …

The role of the local microbial ecosystem in respiratory health and disease

WAA de Steenhuijsen Piters… - … Transactions of the …, 2015 - royalsocietypublishing.org
Respiratory tract infections are a major global health concern, accounting for high morbidity
and mortality, especially in young children and elderly individuals. Traditionally, highly …

“It takes a village”: mechanisms underlying antimicrobial recalcitrance of polymicrobial biofilms

G Orazi, GA O'Toole - Journal of Bacteriology, 2019 - Am Soc Microbiol
Chronic infections are frequently caused by polymicrobial biofilms. Importantly, these
infections are often difficult to treat effectively in part due to the recalcitrance of biofilms to …

The extracellular vesicle generation paradox: a bacterial point of view

HM McMillan, MJ Kuehn - The EMBO Journal, 2021 - embopress.org
All bacteria produce secreted vesicles that carry out a variety of important biological
functions. These extracellular vesicles can improve adaptation and survival by relieving …

[HTML][HTML] Bacterial community interactions during chronic respiratory disease

AL Welp, JM Bomberger - Frontiers in cellular and infection …, 2020 - frontiersin.org
Chronic respiratory diseases including chronic rhinosinusitis, otitis media, asthma, cystic
fibrosis, non-CF bronchiectasis, and chronic obstructive pulmonary disease are a major …

[HTML][HTML] How Streptococcus suis escapes antibiotic treatments

C Uruén, C García, L Fraile, J Tommassen… - Veterinary Research, 2022 - Springer
Streptococcus suis is a zoonotic agent that causes sepsis and meningitis in pigs and
humans. S. suis infections are responsible for large economic losses in pig production. The …