[HTML][HTML] Striatal dopamine neurotransmission: regulation of release and uptake
Dopamine (DA) transmission is governed by processes that regulate release from axonal
boutons in the forebrain and the somatodendritic compartment in midbrain, and by …
boutons in the forebrain and the somatodendritic compartment in midbrain, and by …
Adenosine receptors: expression, function and regulation
Adenosine receptors (ARs) comprise a group of G protein-coupled receptors (GPCR) which
mediate the physiological actions of adenosine. To date, four AR subtypes have been …
mediate the physiological actions of adenosine. To date, four AR subtypes have been …
Astrocyte molecular signatures in Huntington's disease
Astrocytes are implicated in neurodegenerative disorders and may contribute to striatal
neuron loss or dysfunction in Huntington's disease (HD). Here, we assessed striatal …
neuron loss or dysfunction in Huntington's disease (HD). Here, we assessed striatal …
Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits
Background Over the last several years, it has become apparent that there are critical
problems with the hypothesis that brain dopamine (DA) systems, particularly in the nucleus …
problems with the hypothesis that brain dopamine (DA) systems, particularly in the nucleus …
The pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”)
AR Green, AO Mechan, JM Elliott, E O'Shea… - Pharmacological …, 2003 - Elsevier
Abstract The amphetamine derivative (±)-3, 4-methylenedioxymethamphetamine (MDMA,
ecstasy) is a popular recreational drug among young people, particularly those involved in …
ecstasy) is a popular recreational drug among young people, particularly those involved in …
Adenosine and brain function
BB Fredholm, JF Chen, RA Cunha… - Int Rev …, 2005 - books.google.com
A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …
Purinergic signalling: from normal behaviour to pathological brain function
G Burnstock, U Krügel, MP Abbracchio, P Illes - Progress in neurobiology, 2011 - Elsevier
Purinergic neurotransmission, involving release of ATP as an efferent neurotransmitter was
first proposed in 1972. Later, ATP was recognised as a cotransmitter in peripheral nerves …
first proposed in 1972. Later, ATP was recognised as a cotransmitter in peripheral nerves …
[HTML][HTML] Adenosine receptors and brain diseases: neuroprotection and neurodegeneration
Adenosine acts in parallel as a neuromodulator and as a homeostatic modulator in the
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …
Neuroprotection by adenosine in the brain: From A1 receptor activation to A2A receptor blockade
RA Cunha - Purinergic signalling, 2005 - Springer
Adenosine is a neuromodulator that operates via the most abundant inhibitory adenosine A
1 receptors (A 1 Rs) and the less abundant, but widespread, facilitatory A 2A Rs. It is …
1 receptors (A 1 Rs) and the less abundant, but widespread, facilitatory A 2A Rs. It is …
Istradefylline – a first generation adenosine A2A antagonist for the treatment of Parkinson's disease
P Jenner, A Mori, SD Aradi… - Expert Review of …, 2021 - Taylor & Francis
Introduction It is now accepted that Parkinson's disease (PD) is not simply due to
dopaminergic dysfunction, and there is interest in developing non-dopaminergic …
dopaminergic dysfunction, and there is interest in developing non-dopaminergic …