ARF GTPases and their GEFs and GAPs: concepts and challenges
E Sztul, PW Chen, JE Casanova… - Molecular biology of …, 2019 - Am Soc Cell Biol
Detailed structural, biochemical, cell biological, and genetic studies of any gene/protein are
required to develop models of its actions in cells. Studying a protein family in the aggregate …
required to develop models of its actions in cells. Studying a protein family in the aggregate …
Small GTP-binding proteins
Y Takai, T Sasaki, T Matozaki - Physiological reviews, 2001 - journals.physiology.org
Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and
constitute a superfamily consisting of more than 100 members. This superfamily is …
constitute a superfamily consisting of more than 100 members. This superfamily is …
[HTML][HTML] ER-to-Golgi protein delivery through an interwoven, tubular network extending from ER
Cellular versatility depends on accurate trafficking of diverse proteins to their organellar
destinations. For the secretory pathway (followed by approximately 30% of all proteins), the …
destinations. For the secretory pathway (followed by approximately 30% of all proteins), the …
ARF proteins: roles in membrane traffic and beyond
C D'Souza-Schorey, P Chavrier - Nature reviews Molecular cell biology, 2006 - nature.com
The ADP-ribosylation factor (ARF) small GTPases regulate vesicular traffic and organelle
structure by recruiting coat proteins, regulating phospholipid metabolism and modulating the …
structure by recruiting coat proteins, regulating phospholipid metabolism and modulating the …
Synthesis and function of 3-phosphorylated inositol lipids
B Vanhaesebroeck, SJ Leevers… - Annual review of …, 2001 - annualreviews.org
▪ Abstract The 3-phosphorylated inositol lipids fulfill roles as second messengers by
interacting with the lipid binding domains of a variety of cellular proteins. Such interactions …
interacting with the lipid binding domains of a variety of cellular proteins. Such interactions …
[HTML][HTML] Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome
Fragile X syndrome results from the absence of the RNA binding FMR protein. Here, mRNA
was coimmunoprecipitated with the FMRP ribonucleoprotein complex and used to …
was coimmunoprecipitated with the FMRP ribonucleoprotein complex and used to …
Transition of somatic plant cells to an embryogenic state
Under appropriate in vivo or in vitro conditions, certain somatic plant cells have the
capability to initiate embryogenic development (somatic embryogenesis). Somatic …
capability to initiate embryogenic development (somatic embryogenesis). Somatic …
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis
M Mari, J Griffith, E Rieter, L Krishnappa… - Journal of Cell …, 2010 - rupress.org
Eukaryotes use the process of autophagy, in which structures targeted for
lysosomal/vacuolar degradation are sequestered into double-membrane autophagosomes …
lysosomal/vacuolar degradation are sequestered into double-membrane autophagosomes …
Bi-directional protein transport between the ER and Golgi
▪ Abstract The endoplasmic reticulum (ER) and the Golgi comprise the first two steps in
protein secretion. Vesicular carriers mediate a continuous flux of proteins and lipids between …
protein secretion. Vesicular carriers mediate a continuous flux of proteins and lipids between …
[HTML][HTML] Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
Loss of fragile X mental retardation protein (FMRP) function causes the fragile X mental
retardation syndrome. FMRP harbors three RNA binding domains, associates with …
retardation syndrome. FMRP harbors three RNA binding domains, associates with …