Sickle cell disease (SCD) is a group of inherited autosomal recessive disorders, including
sickle cell anemia, sickle beta-thalassemia, and other hemoglobinopathies, which are …

Background Sickle cell disease (SCD) is a genetic disease that impacts patients' quality of
life, healthcare costs, and life expectancy. Elevated sickle hemoglobin (HbS), which readily …

Sickle cell disease (SCD) is a severe monogenic disease associated with high morbidity,
mortality, and a disproportionate burden on Black and Hispanic communities. Our objective …

Summary Sickle Cell Disease (SCD) is an increasing global health problem and presents
significant challenges to European health care systems. Newborn screening (NBS) for SCD …

Sickle cell disease (SCD) is the most common inherited blood disorder in the United States.
It is a medically and socially complex, multisystem illness that affects individuals throughout …

Background This study aimed to evaluate sickle-cell disease (SCD) treatment patterns and
economic burden among patients prescribed hydroxyurea (HU) in the US, through claims …

Context Sickle cell disease (SCD) is a severe hematological disorder. The most common
acute complication of SCD is vaso-occlusive crisis (VOC), but SCD is a systemic disease …

Musculoskeletal pain due to ischemia is present in a variety of clinical conditions including
peripheral vascular disease (PVD), sickle cell disease (SCD), complex regional pain …

Background Sickle cell disease (SCD) may cause several impacts to patients and the whole
society. About 4% of the population has the sickle cell trait in Brazil, and 60,000 to 100,000 …

Sickle cell disease (SCD) presents challenges to hematopoietic stem cell transplantation
(HSCT), including donor availability and morbidity with age/disease severity. However …