Biology of lung macrophages in health and disease
H Aegerter, BN Lambrecht, CV Jakubzick - Immunity, 2022 - cell.com
Tissue-resident alveolar and interstitial macrophages and recruited macrophages are critical
players in innate immunity and maintenance of lung homeostasis. Until recently, assessing …
players in innate immunity and maintenance of lung homeostasis. Until recently, assessing …
Tissue-resident immunity in the lung: a first-line defense at the environmental interface
The lung is a vital organ that incessantly faces external environmental challenges. Its
homeostasis and unimpeded vital function are ensured by the respiratory epithelium …
homeostasis and unimpeded vital function are ensured by the respiratory epithelium …
Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDA) orchestrates a suppressive tumor
microenvironment that fosters immunotherapy resistance. Tumor-associated macrophages …
microenvironment that fosters immunotherapy resistance. Tumor-associated macrophages …
The World according to IL-9
Among the cytokines regulating immune cells, IL-9 has gained considerable attention for its
ability to act on multiple cell types as a regulator of beneficial and pathologic immune …
ability to act on multiple cell types as a regulator of beneficial and pathologic immune …
The role of macrophages in non-small cell lung cancer and advancements in 3D co-cultures
Lung cancer (LC) is the leading cause of cancer-related deaths worldwide. Traditional
therapeutic approaches such as chemotherapy or radiotherapy have provided only a …
therapeutic approaches such as chemotherapy or radiotherapy have provided only a …
The Role of Stroma in Cancer Metabolism
AC Kimmelman, MH Sherman - Cold Spring …, 2024 - perspectivesinmedicine.cshlp.org
The altered metabolism of tumor cells is a well-known hallmark of cancer and is driven by
multiple factors such as mutations in oncogenes and tumor suppressor genes, the origin of …
multiple factors such as mutations in oncogenes and tumor suppressor genes, the origin of …
The dichotomy of interleukin-9 function in the tumor microenvironment
A Cannon, A Pajulas, MH Kaplan… - Journal of Interferon & …, 2023 - liebertpub.com
Interleukin 9 (IL-9) is a cytokine with potent proinflammatory properties that plays a central
role in pathologies such as allergic asthma, immunity to parasitic infection, and …
role in pathologies such as allergic asthma, immunity to parasitic infection, and …
[HTML][HTML] Pristane attenuates atherosclerosis in Apoe−/− mice via IL-4-secreting regulatory plasma cell-mediated M2 macrophage polarization
Y Huang, K Ma, R Qin, Y Fang, J Zhou, X Dai - Biomedicine & …, 2022 - Elsevier
Atherosclerosis, an inflammatory progressive vascular disease, causes heart disease and
stroke worldwide. B cells with immune suppressive functions have been implicated in …
stroke worldwide. B cells with immune suppressive functions have been implicated in …
[HTML][HTML] Shenhuang plaster ameliorates the inflammation of postoperative ileus through inhibiting PI3K/Akt/NF-κB pathway
T Liu, M Xu, Z Shi, M Li, R Wang, Y Shi, X Xu… - Biomedicine & …, 2022 - Elsevier
Abstract Background Although Shenhuang plaster (SHP) from traditional Chinese medicine
prescriptions, has the potential to promote the recovery progression of postoperative ileus …
prescriptions, has the potential to promote the recovery progression of postoperative ileus …
[HTML][HTML] IL-9 stimulates an anti-tumor immune response and facilitates immune checkpoint blockade in the CMT167 mouse model
Y Feng, S Yan, SK Lam, FCF Ko, C Chen, M Khan… - Lung Cancer, 2022 - Elsevier
Objectives There is mounting evidence that interleukin-9 (IL-9) is associated with various
cancers although its function in lung cancer remains elusive. This study aimed to elucidate …
cancers although its function in lung cancer remains elusive. This study aimed to elucidate …