The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …

In this study, a new series of N-acyl hydrazones 7a-e, 8a-e, and 9a-e, starting from methyl δ-
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …

Aim: To enrich the pool of α-amylase inhibitors to manage Type 2 diabetes. Methods:
Synthesis, conformational study, α-amylase inhibitory action and various in silico studies of …

Chinese herbal medicine and Chinese patent medicine have been widely applied for cancer
care in China. Rupestonic acid, an active ingredient of Artemisia rupestris L., has recently …

Hydrazide-hydrazones are condensation products of carboxylic acid hydrazides and
aldehydes. These compounds are an important class of organic compounds of interest to …

The current anticancer therapy strategy that can be done is chemotherapy. Although
cisplatin has become a common drug for the clinical treatment of solid tumors, its use has …