The yeast Saccharomyces cerevisiae has been a favorite organism for pioneering studies
on nutrient-sensing and signaling mechanisms. Many specific nutrient responses have been …

The cAMP–protein kinase A (PKA) pathway in the yeast Saccharomyces cerevisiae plays a
major role in the control of metabolism, stress resistance and proliferation, in particular in …

Yeast and cancer cells share the unusual characteristic of favoring fermentation of sugar
over respiration. We now reveal an evolutionary conserved mechanism linking fermentation …

Glucose has dramatic effects on the regulation of carbon metabolism and on many other
properties of yeast cells. Several sensing and signalling pathways are involved. For many …

Although sugars are clearly the preferred carbon sources of the yeast Saccharomyces
cerevisiae, nonfermentable substrates such as ethanol, glycerol, lactate, acetate or oleate …

In the yeast Saccharomyces cerevisiae the accumulation of cAMP is controlled by an
elaborate pathway. Only two triggers of the Ras adenylate cyclase pathway are known …

Cells of all living organisms contain complex signal transduction networks to ensure that a
wide range of physiological properties are properly adapted to the environmental conditions …

Adenylate cyclase activity in Saccharomyces cerevisiae is dependent on Ras proteins. Both
addition of glucose to glucose‐deprived (derepressed) cells and intracellular acidification …

Two well characterized signal transduction cascades regulating fungal development and
virulence are the MAP kinase and cAMP signaling cascades. Here we review the current …

In Saccharomyces cerevisiae, glucose activation of cAMP synthesis requires both the
presence of the G‐protein‐coupled receptor (GPCR) system, Gpr1‐Gpa2, and uptake and …