The multifaceted role of the ventromedial prefrontal cortex in emotion, decision making, social cognition, and psychopathology

J Hiser, M Koenigs - Biological psychiatry, 2018 - Elsevier
The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of social,
cognitive, and affective functions that are commonly disrupted in mental illness. In this …

Inhibition and the right inferior frontal cortex: one decade on

AR Aron, TW Robbins, RA Poldrack - Trends in cognitive sciences, 2014 - cell.com
In our TICS Review in 2004, we proposed that a sector of the right inferior frontal cortex
(rIFC) in humans is critical for inhibiting response tendencies. Here we survey new …

Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior

EA Ferenczi, KA Zalocusky, C Liston, L Grosenick… - Science, 2016 - science.org
INTRODUCTION The drive to seek and experience reward is conserved across species and,
in mammals, involves interactions between subcortical dopaminergic systems and limbic …

Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking

BT Chen, HJ Yau, C Hatch, I Kusumoto-Yoshida… - Nature, 2013 - nature.com
Loss of control over harmful drug seeking is one of the most intractable aspects of addiction,
as human substance abusers continue to pursue drugs despite incurring significant negative …

Lateral hypothalamus, nucleus accumbens, and ventral pallidum roles in eating and hunger: interactions between homeostatic and reward circuitry

DC Castro, SL Cole, KC Berridge - Frontiers in systems neuroscience, 2015 - frontiersin.org
The study of the neural bases of eating behavior, hunger, and reward has consistently
implicated the lateral hypothalamus (LH) and its interactions with mesocorticolimbic circuitry …

A dual operator view of habitual behavior reflecting cortical and striatal dynamics

KS Smith, AM Graybiel - Neuron, 2013 - cell.com
Habits are notoriously difficult to break and, if broken, are usually replaced by new routines.
To examine the neural basis of these characteristics, we recorded spike activity in cortical …

Differential roles of medial prefrontal subregions in the regulation of drug seeking

DE Moorman, MH James, EM McGlinchey… - Brain research, 2015 - Elsevier
The prefrontal cortex plays an important role in shaping cognition and behavior. Many
studies have shown that medial prefrontal cortex (mPFC) plays a key role in seeking …

Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model

MC Anderson, SB Floresco - Neuropsychopharmacology, 2022 - nature.com
Neuroimaging has revealed robust interactions between the prefrontal cortex and the
hippocampus when people stop memory retrieval. Efforts to stop retrieval can arise when …

A systematic review of neural, cognitive, and clinical studies of anger and aggression

Y Richard, N Tazi, D Frydecka, MS Hamid… - Current …, 2023 - Springer
Anger and aggression have large impact on people's safety and the society at large. In order
to provide an intervention to minimise aggressive behaviours, it is important to understand …

Prelimbic and infralimbic prefrontal regulation of active and inhibitory avoidance and reward-seeking

G Capuzzo, SB Floresco - Journal of Neuroscience, 2020 - Soc Neuroscience
Flexible initiation or suppression of actions to avoid aversive events is crucial for survival.
The prelimbic (PL) and infralimbic (IL) regions of the medial prefrontal cortex (mPFC) have …