Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

Bone biomaterials play a vital role in bone repair by providing the necessary substrate for
cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In …

The microenvironments with high reactive-oxygen-species (ROS) levels, inflammatory
responses, and oxidative-stress effects in diabetic ulcer wounds, leading to poor …

Diabetic foot ulcers (DFUs) are one of the most common and serious complications of
diabetes mellitus, as wound healing is impaired in the diabetic foot. Wound healing is a …

Chronic diabetic wounds represent a huge socioeconomic burden for both affected
individuals and the entire healthcare system. Although the number of available treatment …

Mesenchymal stem cells (MSCs), an ideal cell source for regenerative therapy with no
ethical issues, play an important role in diabetic foot ulcer (DFU). Growing evidence has …

Background Diabetic foot ulcer (DFU) is a severe complication of diabetes, preceding most
diabetes-related amputations. DFUs require over US $9 billion for yearly treatment and are …

Excessive expression of matrix metalloproteinase 9 (MMP-9) impedes healing of diabetic
chronic wounds, thus wound dressing that could effectively inhibit the expression of MMP-9 …

Diabetic foot ulcer has become a worldwide clinical medical challenge as traditional
treatments are not effective enough to reduce the amputation rate. Therefore, it is of great …

One of the most common complications of diabetes is diabetic foot ulcer. Diabetic ulcers do
not heal easily due to diabetic neuropathy and reduced blood flow, and nonhealing ulcers …