Daphnia as a versatile model system in ecology and evolution

D Ebert - EvoDevo, 2022 - Springer
Water fleas of the genus Daphnia have been a model system for hundreds of years and is
among the best studied ecological model organisms to date. Daphnia are planktonic …

Long-term balancing selection for pathogen resistance maintains trans-species polymorphisms in a planktonic crustacean

L Cornetti, PD Fields, L Du Pasquier, D Ebert - Nature Communications, 2024 - nature.com
Balancing selection is an evolutionary process that maintains genetic polymorphisms at
selected loci and strongly reduces the likelihood of allele fixation. When allelic …

Dominance and multi-locus interaction

J Li, C Bank - Trends in Genetics, 2024 - cell.com
Dominance is usually considered a constant value that describes the relative difference in
fitness or phenotype between heterozygotes and the average of homozygotes at a focal …

Genetic drift shapes the evolution of a highly dynamic metapopulation

P Angst, C Ameline, CR Haag… - Molecular Biology …, 2022 - academic.oup.com
The dynamics of extinction and (re) colonization in habitat patches are characterizing
features of dynamic metapopulations, causing them to evolve differently than large, stable …

QTL study reveals candidate genes underlying host resistance in a Red Queen model system

M Fredericksen, PD Fields, L Du Pasquier, V Ricci… - PLoS …, 2023 - journals.plos.org
Specific interactions of host and parasite genotypes can lead to balancing selection,
maintaining genetic diversity within populations. In order to understand the drivers of such …

Parasitoid Serpins Evolve Novel Functions to Manipulate Host Homeostasis

Z Wu, R Yuan, Q Gu, X Wu, L Gu, X Ye… - Molecular Biology …, 2023 - academic.oup.com
Parasitoids introduce various virulence factors when parasitism occurs, and some taxa
generate teratocytes to manipulate the host immune system and metabolic homeostasis for …

Uncovering the genomic basis of infection through co-genomic sequencing of hosts and parasites

E Dexter, PD Fields, D Ebert - Molecular Biology and Evolution, 2023 - academic.oup.com
Understanding the genomic basis of infectious disease is a fundamental objective in co-
evolutionary theory with relevance to healthcare, agriculture, and epidemiology. Models of …

The role of rock matrix permeability in controlling hydraulic fracturing in sandstones

M Fazio, P Ibemesi, P Benson… - Rock Mechanics and …, 2021 - Springer
A concomitant effect of a hydraulic fracturing experimenting is frequently fluid permeation
into the rock matrix, with the injected fluid permeating through the porous rock matrix (leak …

Population-Genomic Analysis Identifies a Low Rate of Global Adaptive Fixation in the Proteins of the Cyclical Parthenogen Daphnia magna

PD Fields, S McTaggart, CMO Reisser… - Molecular Biology …, 2022 - academic.oup.com
Daphnia are well-established ecological and evolutionary models, and the interaction
between D. magna and its microparasites is widely considered a paragon of the host …

Novel genomic approaches to study antagonistic coevolution between hosts and parasites

H Märkle, S John, A Cornille, PD Fields… - Molecular …, 2021 - Wiley Online Library
Host‐parasite coevolution is ubiquitous, shaping genetic and phenotypic diversity and the
evolutionary trajectory of interacting species. With the advances of high throughput …