Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Tumor-derived exosomal non-coding RNAs as diagnostic biomarkers in cancer

N Ebrahimi, F Faghihkhorasani, SS Fakhr… - Cellular and Molecular …, 2022 - Springer
Almost all clinical oncologists agree that the discovery of reliable, accessible, and non-
invasive biomarkers is necessary to decrease cancer mortality. It is possible to employ …

Mechanistic action of cell cycle arrest and intrinsic apoptosis via inhibiting Akt/mTOR and activation of p38-MAPK signaling pathways in Hep3B liver cancer cells by …

A Abusaliya, SH Jeong, PB Bhosale, HH Kim, MY Park… - Nutrients, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) has a poor prognosis and a low survival rate. Drugs
without side effects are desperately needed since chemotherapy has a negative effect on …

[HTML][HTML] Circular RNA circPBX3 promotes cisplatin resistance of ovarian cancer cells via interacting with IGF2BP2 to stabilize ATP7A mRNA expression

L Fu, D Zhang, N Yi, Y Cao, Y Wei, W Wang, L Li - Human Cell, 2022 - Springer
Circular RNAs (circRNAs) are a class of non-coding RNAs with a unique covalently closed
loop structure. Recent studies indicate that dysregulation of circRNAs acts a role in cancer …

Non-coding RNAs as key regulators of Gasdermin-D mediated pyroptosis in cancer therapy

G Gupta, M Afzal, E Moglad, H Ali, TG Singh… - … -Research and Practice, 2024 - Elsevier
Pyroptosis is an inflammatory programed cell death process that plays a crucial role in
cancer therapeutic, while Gasdermin-D is a critical effector protein for pyroptosis execution …

LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis

W Huang, H Zhang, Y Tian, Y Li, J Li, X Zhong… - Anti-Cancer …, 2022 - journals.lww.com
Long noncoding RNAs (lncRNAs) have been reported to serve as vital regulators in the
chemoresistance of human cancers, including colorectal cancer (CRC). In this study, we …

MicroRNA-25-3p promotes cisplatin resistance in non-small-cell lung carcinoma (NSCLC) through adjusting PTEN/PI3K/AKT route

B Sun, N Hu, D Cong, K Chen, J Li - Bioengineered, 2021 - Taylor & Francis
MicroRNAs exert crucial effects in the drug resistance. The purpose of this research was to
investigate the miR-25-3p effects on DDP resistance in NSCLC. We used RT-qPCR to …

Regulation of the cell cycle by ncRNAs affects the efficiency of CDK4/6 inhibition

Q Hu, T Huang - International Journal of Molecular Sciences, 2023 - mdpi.com
Cyclin-dependent kinases (CDKs) regulate cell division at multiple levels. Aberrant
proliferation induced by abnormal cell cycle is a hallmark of cancer. Over the past few …

Implication of miR-122, miR-483, and miR-335 expression levels as potential signatures in HCV-related hepatocellular carcinoma (HCC) in Egyptian patients

AY Elfert, A Salem, AM Abdelhamid… - Frontiers in Molecular …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related
deaths worldwide with chronic hepatitis C virus (HCV) infection as a major risk factor of …

[HTML][HTML] LncRNA MCM3AP-AS1 promotes chemoresistance in triple-negative breast cancer through the miR-524-5p/RBM39 axis

Y Wang, X Wang, H Sun, Z Zhang, J Gu - Molecular and Cellular …, 2024 - Springer
Triple-negative breast cancer (TNBC) is the most lethal subtype of BC, with unfavorable
treatment outcomes. Evidence suggests the engagement of lncRNA MCM3AP-AS1 in BC …