The programmed cell death 1 (PD-1) pathway is an important regulator of immune
responses in peripheral tissues, including abnormal situations such as the tumor …

The galectin family consists of carbohydrate (glycan) binding proteins that are expressed by
a wide variety of cells and bind to galactose-containing glycans. Galectins can be located in …

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), the
causative agent of coronavirus disease 2019 (COVID-19), has been declared a global …

Essentially all cells are covered with a dense coat of different glycan structures/sugar chains,
giving rise to the so‐called glycocalyx. Changes in cellular glycosylation are a hallmark of …

Galectin-3 (Gal-3), a beta-galactoside-binding lectin, plays a pivotal role in various cellular
processes, including immune responses, inflammation, and cancer progression. This …

Abstract Galectin-3 (Gal3) is a multifaceted protein which belongs to a family of lectins and
binds β-galactosides. Gal3 expression is altered in many types of cancer, with increased …

In the galectin family, a group of lectins is united by their evolutionarily conserved
carbohydrate recognition domains. These polypeptides play a role in various cellular …

Severe coronavirus disease 2019 (COVID-19) is associated with hyperinflammation leading
to organ injury, including respiratory failure. Galectin-3 was implicated in innate …

Periodontal diseases are chronic inflammatory diseases that occur due to the imbalance
between microbial communities in the oral cavity and the immune response of the host that …

Glycosylation is an important post-translational modification, giving rise to a diverse and
abundant repertoire of glycans on the cell surface, collectively known as the glycome. When …