Screening of transcription factors involved in fetal hemoglobin regulation using phylogenetic footprinting
GC de Souza Carrocini, LPR Venancio… - Evolutionary …, 2015 - journals.sagepub.com
Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies.
The regulation of Hb F levels is influenced by transcription factors. We used phylogenetic …
The regulation of Hb F levels is influenced by transcription factors. We used phylogenetic …
Gene expression analysis of the Brazilian type of hereditary persistence of fetal hemoglobin: identification of genes that could be related to γ-Globin activation
FM Roversi, AF da Cunha, AF Brugnerotto… - …, 2013 - Taylor & Francis
Increased γ-globin production and consequent fetal hemoglobin (Hb F, α2γ2) formation is an
important modulator of the clinical and hematological features of hemolytic anemias, such as …
important modulator of the clinical and hematological features of hemolytic anemias, such as …
New deletion at promoter of HBG1 gene in sickle cell disease patients with high HbF level
L Chaouch, H Sellami, M Kalai, I Darragi… - Journal of Pediatric …, 2020 - journals.lww.com
Objectives: The 5′ upstream region of the HBG1 gene plays a very important role in the
expression of fetal hemoglobin (HbF). In contrast, increased HbF levels can inhibit the …
expression of fetal hemoglobin (HbF). In contrast, increased HbF levels can inhibit the …
Etiologia molecular de hemoglobinopatias raras
EPP da Silva - 2022 - search.proquest.com
As hemoglobinopatias referem-se a patologias associadas a alterações moleculares nos
genes das globinas e podem ser classificadas como variantes da hemoglobina ou …
genes das globinas e podem ser classificadas como variantes da hemoglobina ou …