Automation and data-driven design of polymer therapeutics

R Upadhya, S Kosuri, M Tamasi, TA Meyer… - Advanced drug delivery …, 2021 - Elsevier
Polymers are uniquely suited for drug delivery and biomaterial applications due to tunable
structural parameters such as length, composition, architecture, and valency. To facilitate …

High-throughput routes to biomaterials discovery

F Soheilmoghaddam, M Rumble… - Chemical …, 2021 - ACS Publications
Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …

[HTML][HTML] Operator-independent high-throughput polymerization screening based on automated inline NMR and online SEC

J Van Herck, I Abeysekera, AL Buckinx, K Cai… - Digital …, 2022 - pubs.rsc.org
Traditional protocols for high-throughput screening and experimentation are inherently time-
consuming and cost-ineffective. Herein, we present a continuous flow-based automated …

Screening RAFT agents and photocatalysts to mediate PET-RAFT polymerization using a high throughput approach

G Ng, K Jung, J Li, C Wu, L Zhang, C Boyer - Polymer Chemistry, 2021 - pubs.rsc.org
We report a high throughput approach for the screening of RAFT agents and photocatalysts
to mediate photoinduced electron/energy transfer-reversible addition–fragmentation chain …

Application of Digital Methods in Polymer Science and Engineering

T Schuett, P Endres, T Standau… - Advanced Functional …, 2024 - Wiley Online Library
The development of new polymer materials is an emerging field for more than 100 years.
However, it is currently facing major challenges and the application of digital methods can …

Streamlining the Generation of Advanced Polymer Materials Through the Marriage of Automation and Multiblock Copolymer Synthesis in Emulsion

GKK Clothier, TR Guimarães… - Angewandte …, 2024 - Wiley Online Library
Synthetic polymers are of paramount importance in modern life‐an incredibly wide range of
polymeric materials possessing an impressive variety of properties have been developed to …

[HTML][HTML] Synthesis of functional miktoarm star polymers in an automated parallel synthesizer

C Chen, F Richter, J Zhang, C Guerrero-Sanchez… - European Polymer …, 2021 - Elsevier
A feasibility study for the synthesis of well-defined miktoarm star polymers containing
peptide arms in an automated parallel synthesizer is reported. A series of linear homo-and …

Biomass crosslinked fluorinated methacrylate elastomer for stress sensors with recyclability, reprocessability, remoldability, and hydrophobicity

Z Xia, Z Feng, Z Niu, J He, W Fan, C Bai - European Polymer Journal, 2024 - Elsevier
Fluorinated copolymers typically exhibit exceptional chemical inertness and interesting
surface properties. However, the failure to further enhance the mechanical properties of …

Tough, Hydrophobic, Pressure-Resistant, and Self-Cleaning Underwater Engineering Materials Based on Copolymerization of Butadiene and Trifluoroethyl …

Z Xia, Z Feng, R Wu, Z Niu, J He… - ACS Applied Polymer …, 2023 - ACS Publications
In recent years, the further development and utilization of marine resources have led to a
great deal of attention being paid to elastomer materials with hydrophobic and pressure …

[HTML][HTML] Glycerol methacrylate-based copolymers: Reactivity ratios, physicochemical characterization and cytotoxicity

C Ventura-Hunter, VD Lechuga-Islas, J Ulbrich… - European Polymer …, 2022 - Elsevier
Understanding the chemical composition of biocompatible copolymers is crucial for diverse
biomedical applications such as the conjugation of polymers to drugs, peptides or proteins …