Gene environment interactions in the etiology of neural tube defects
RH Finnell, CD Caiaffa, SE Kim, Y Lei, J Steele… - Frontiers in …, 2021 - frontiersin.org
Human structural congenital malformations are the leading cause of infant mortality in the
United States. Estimates from the United States Center for Disease Control and Prevention …
United States. Estimates from the United States Center for Disease Control and Prevention …
Progress report on new antiepileptic drugs: a summary of the Twelfth Eilat Conference (EILAT XII)
M Bialer, SI Johannessen, RH Levy, E Perucca… - Epilepsy research, 2015 - Elsevier
Summary The Twelfth Eilat Conference on New Antiepileptic Drugs (AEDs)–EILAT XII, took
place in Madrid, Spain from August 31st to September 3rd 2014. About 130 basic scientists …
place in Madrid, Spain from August 31st to September 3rd 2014. About 130 basic scientists …
Progress report on new antiepileptic drugs: a summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII)
M Bialer, SI Johannessen, RH Levy, E Perucca… - …, 2017 - Wiley Online Library
Summary The Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT
XIII) took place in Madrid, Spain, on June 26–29, 2016, and was attended by> 200 …
XIII) took place in Madrid, Spain, on June 26–29, 2016, and was attended by> 200 …
A resurging boom in new drugs for epilepsy and brain disorders
Introduction: Epilepsy is one of the most common neurological diseases affecting
approximately 50 million people worldwide. Despite many advances in epilepsy research …
approximately 50 million people worldwide. Despite many advances in epilepsy research …
Recent advances in status epilepticus
Recent advances in status epilepticus : Current Opinion in Neurology Recent advances in
status epilepticus : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …
status epilepticus : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …
[HTML][HTML] Novel drugs and early polypharmacotherapy in status epilepticus
M Amengual-Gual, IS Fernández, MS Wainwright - Seizure, 2019 - Elsevier
Purpose Rescue medications for status epilepticus (SE) have a relatively high rate of failure.
The purpose of this review is to summarize the evidence for the efficacy of novel drugs and …
The purpose of this review is to summarize the evidence for the efficacy of novel drugs and …
Moving beyond sodium valproate: choosing the right anti-epileptic drug in children
G Balagura, G Iapadre, A Verrotti… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Sodium valproate is a widely used anti-epileptic drug with a broad spectrum of
activity and mechanism of action. It has consequently been the first-line drug for most …
activity and mechanism of action. It has consequently been the first-line drug for most …
Mitochondrial liver toxicity of valproic acid and its acid derivatives is related to inhibition of α-lipoamide dehydrogenase
AP Kudin, H Mawasi, A Eisenkraft, CE Elger… - International Journal of …, 2017 - mdpi.com
The liver toxicity of valproic acid (VPA) is an established side effect of this widely used
antiepileptic drug, which is extremely problematic for patients with metabolic epilepsy and …
antiepileptic drug, which is extremely problematic for patients with metabolic epilepsy and …
Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice
YL Lin, M Bialer, RM Cabrera, RH Finnell… - Birth Defects …, 2019 - Wiley Online Library
Objectives The anticonvulsant valproic acid (VPA) has a known teratogenic effect capable of
inducing major congenital malformations and developmental disorders. A comparative …
inducing major congenital malformations and developmental disorders. A comparative …
[HTML][HTML] Amidic derivatives of valproic acid, valpromide and valnoctamide, inhibit HSV-1 infection in oligodendrocytes
B Praena, R Bello-Morales, F de Castro… - Antiviral Research, 2019 - Elsevier
Herpes simplex virus type 1 (HSV-1) is a ubiquitous infectious agent that can establish
latency in neurons, and in some cases, viral retrograde transport results in infection of the …
latency in neurons, and in some cases, viral retrograde transport results in infection of the …