An update on red blood cell storage lesions, as gleaned through biochemistry and omics technologies
Red blood cell (RBC) aging in the blood bank is characterized by the accumulation of a
significant number of biochemical and morphologic alterations. Recent mass spectrometry …
significant number of biochemical and morphologic alterations. Recent mass spectrometry …
[HTML][HTML] Blood microvesicles: from proteomics to physiology
JD Tissot, G Canellini, O Rubin… - Translational …, 2013 - Elsevier
Phospholipid vesicles of less than 1 μm are present in blood in physiological state and their
concentration may vary under pathological conditions. Various names such as exosomes …
concentration may vary under pathological conditions. Various names such as exosomes …
Alterations of red blood cell metabolome during cold liquid storage of erythrocyte concentrates in CPD–SAGM
Erythrocyte concentrates for transfusion purposes represent a life-saving therapeutics of
primary relevance in the clinical setting. However, efforts have been continuously proposed …
primary relevance in the clinical setting. However, efforts have been continuously proposed …
Glucose 6-phosphate dehydrogenase deficient subjects may be better “storers” than donors of red blood cells
Storage of packed red blood cells (RBCs) is associated with progressive accumulation of
lesions, mostly triggered by energy and oxidative stresses, which potentially compromise the …
lesions, mostly triggered by energy and oxidative stresses, which potentially compromise the …
Biophysical and biochemical markers of red blood cell fragility
A Orbach, O Zelig, S Yedgar, G Barshtein - Transfusion Medicine and …, 2017 - karger.com
Summary Background: Red blood cells (RBCs) undergo a natural aging process occurring
in the blood circulation throughout the RBC lifespan or during routine cold storage in the …
in the blood circulation throughout the RBC lifespan or during routine cold storage in the …
[HTML][HTML] Involvement of calcium, reactive oxygen species, and ATP in hexavalent chromium-induced damage in red blood cells
R Zhang, Y Xiang, Q Ran, X Deng, Y Xiao… - Cellular Physiology and …, 2014 - karger.com
Aim: The aim of this study was to investigate the mechanisms of Cr 6+-induced red blood
cells (RBCs) damage. Methods: The effect of Cr 6+ exposure on RBCs was evaluated by …
cells (RBCs) damage. Methods: The effect of Cr 6+ exposure on RBCs was evaluated by …
Erythrocyte's aging in microgravity highlights how environmental stimuli shape metabolism and morphology
The determination of the function of cells in zero-gravity conditions is a subject of interest in
many different research fields. Due to their metabolic unicity, the characterization of the …
many different research fields. Due to their metabolic unicity, the characterization of the …
Protect, repair, destroy or sacrifice: a role of oxidative stress biology in inter-donor variability of blood storage?
A D'Alessandro, KC Hansen… - Blood …, 2018 - pmc.ncbi.nlm.nih.gov
Red blood cells (RBCs) have been historically regarded as a critical model to investigate
cellular and oxidant stress biology. First of all, they are constantly exposed to oxidant stress …
cellular and oxidant stress biology. First of all, they are constantly exposed to oxidant stress …
Storage-induced damage to red blood cell mechanical properties can be only partially reversed by rejuvenation
G Barshtein, A Gural, N Manny, O Zelig… - Transfusion medicine …, 2014 - karger.com
Background: The storage of red blood cells (RBC) is associated with impairment of their
properties that can induce a circulatory risk to recipients. In a preceding study (2009), we …
properties that can induce a circulatory risk to recipients. In a preceding study (2009), we …
Surprising structural and functional properties of Favism erythrocytes are linked to special metabolic regulation: a cell aging study
S Dinarelli, G Longo, S Germanova-Taneva… - International Journal of …, 2022 - mdpi.com
Favism uniquely arises from a genetic defect of the Glucose-6 Phosphate Dehydrogenase
(G6PD) enzyme and results in a severe reduction of erythrocytes'(RBCs) reducing power …
(G6PD) enzyme and results in a severe reduction of erythrocytes'(RBCs) reducing power …