African swine fever virus: a review

Z Li, W Chen, Z Qiu, Y Li, J Fan, K Wu, X Li, M Zhao… - Life, 2022 - mdpi.com
African swine fever (ASF) is a viral disease with a high fatality rate in both domestic pigs and
wild boars. ASF has greatly challenged pig-raising countries and also negatively impacted …

Vaccines for African swine fever: An update

H Zhang, S Zhao, H Zhang, Z Qin, H Shan… - Frontiers in …, 2023 - frontiersin.org
African swine fever (ASF) is a fatal infectious disease of swine caused by the African swine
fever virus (ASFV). Currently, the disease is listed as a legally notifiable disease that must be …

Evaluation of an I177L gene-based five-gene-deleted African swine fever virus as a live attenuated vaccine in pigs

Y Liu, Z Xie, Y Li, Y Song, D Di, J Liu… - Emerging Microbes & …, 2023 - Taylor & Francis
African swine fever (ASF) is a highly contagious disease of domestic and wild pigs caused
by the African swine fever virus (ASFV). The current research on ASF vaccines focuses on …

Immunoinformatics-guided approach for designing a pan-proteome multi-epitope subunit vaccine against African swine fever virus

AM Simbulan, EC Banico, EMJS Sira… - Scientific Reports, 2024 - nature.com
Despite being identified over a hundred years ago, there is still no commercially available
vaccine for the highly contagious and deadly African swine fever virus (ASFV). This study …

The attenuated African swine fever vaccine HLJ/18-7GD provides protection against emerging prevalent genotype II variants in China

Z Wang, J Zhang, F Li, Z Zhang, W Chen… - Emerging Microbes & …, 2024 - Taylor & Francis
Genetic changes have occurred in the genomes of prevalent African swine fever viruses
(ASFVs) in the field in China, which may change their antigenic properties and result in …

Recent progress on gene-deleted live-attenuated African swine fever virus vaccines

HLX Vu, DS McVey - npj Vaccines, 2024 - nature.com
Abstract African Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality
rates approaching 100%. The disease has spread to many swine-producing countries …

African swine fever virus: A re-emerging threat to the swine industry and food security in the Americas

J Ruiz-Saenz, A Diaz, DK Bonilla-Aldana… - Frontiers in …, 2022 - frontiersin.org
African swine fever (ASF) is a devastating disease for the swine industry, characterized by
hemorrhagic fever with up to 100% mortality rate, and with a tremendous socioeconomic …

ASF vaccine candidate ASFV-G-∆ I177L does not exhibit residual virulence in long-term clinical studies

MV Borca, E Ramirez-Medina, E Silva, A Rai… - Pathogens, 2023 - mdpi.com
African swine fever (ASF) is an important disease in swine currently producing a pandemic
affecting pig production worldwide. Except in Vietnam, where two vaccines were recently …

Deletion of the H108R gene reduces virulence of the pandemic Eurasia strain of African swine fever virus with surviving animals being protected against virulent …

E Vuono, E Ramirez-Medina, E Silva, A Rai… - Journal of …, 2022 - Am Soc Microbiol
African swine fever virus (ASFV) is the etiological agent of African swine fever (ASF), a
devastating disease affecting domestic and wild swine and currently causing a global …

African swine fever vaccine candidate ASFV-G-ΔI177L produced in the swine macrophage-derived cell line IPKM remains genetically stable and protective against …

MV Borca, A Rai, N Espinoza, E Ramirez-Medina… - Viruses, 2023 - mdpi.com
ASFV vaccine candidate ASFV-G-ΔI177L has been shown to be highly efficacious in
inducing protection against challenges with the parental virus, the Georgia 2010 isolate, as …