For the past two decades, the function of intrabony nerves on bone has been a subject of
intense research, while the function of bone on intrabony nerves is still hidden in the corner …

It is from the discovery of leptin and the central nervous system as a regulator of bone
remodeling that the presence of autonomic nerves within the skeleton transitioned from a …

Bone and lung metastases are responsible for the majority of deaths in patients with breast
cancer. Following treatment of the primary cancer, emotional and psychosocial factors within …

Loss of body weight is associated with bone loss, and body weight gain is associated with
increased bone formation. The molecular mechanisms linking body weight, body …

The skeleton is no longer seen as a static, isolated, and mostly structural organ. Over the last
two decades, a more complete picture of the multiple functions of the skeleton has emerged …

It has been demonstrated that human osteoblastic as well as osteoclastic cells are equipped
with adrenergic receptors and neuropeptide receptors and that they constitutively express …

BACKGROUND. Evidence from rodent studies indicates that the sympathetic nervous
system (SNS) regulates bone metabolism, principally via β2-adrenergic receptors (β2-ARs) …

Changes in whole body energy levels are closely linked to alterations in body weight and
bone mass. Here, we show that hypothalamic signals contribute to the regulation of bone …

An increasing number of studies suggest that nerve-derived signals play an important role in
the regulation of bone remodeling. Neuropeptides and receptors/transporters of adrenergic …

Glucocorticoids are widely used to treat various inflammatory lung diseases. Acting via the
glucocorticoid receptor (GR), they exert clinical effects predominantly by modulating gene …