The current landscape of NKT cell immunotherapy and the hills ahead
Simple Summary Natural killer T (NKT) cells are a subset of lipid-reactive T cells that
enhance anti-tumor immunity. While preclinical studies have shown NKT cell …
enhance anti-tumor immunity. While preclinical studies have shown NKT cell …
CAR-NKT cell therapy: a new promising paradigm of cancer immunotherapy
Today, cancer treatment is one of the fundamental problems facing clinicians and
researchers worldwide. Efforts to find an excellent way to treat this illness continue, and new …
researchers worldwide. Efforts to find an excellent way to treat this illness continue, and new …
Microneedle‐assisted transdermal delivery of nanoparticles: Recent insights and prospects
AJ Guillot, M Martínez‐Navarrete… - Wiley …, 2023 - Wiley Online Library
Transdermal delivery of drugs offers an interesting alternative for the administration of
molecules that present certain troubles when delivered by the oral route. It can produce …
molecules that present certain troubles when delivered by the oral route. It can produce …
Toll-like receptor-targeted anti-tumor therapies: Advances and challenges
Y Yang, H Li, C Fotopoulou, P Cunnea… - Frontiers in …, 2022 - frontiersin.org
Toll-like receptors (TLRs) are pattern recognition receptors, originally discovered to
stimulate innate immune reactions against microbial infection. TLRs also play essential roles …
stimulate innate immune reactions against microbial infection. TLRs also play essential roles …
The role of toll-like receptor agonists and their nanomedicines for tumor immunotherapy
L Huang, X Ge, Y Liu, H Li, Z Zhang - Pharmaceutics, 2022 - mdpi.com
Toll-like receptors (TLRs) are a class of pattern recognition receptors that play a critical role
in innate and adaptive immunity. Toll-like receptor agonists (TLRa) as vaccine adjuvant …
in innate and adaptive immunity. Toll-like receptor agonists (TLRa) as vaccine adjuvant …
Carbohydrate conjugates in vaccine developments
S Lang, X Huang - Frontiers in Chemistry, 2020 - frontiersin.org
Vaccines are powerful tools that can activate the immune system for protection against
various diseases. As carbohydrates can play important roles in immune recognition, they …
various diseases. As carbohydrates can play important roles in immune recognition, they …
[HTML][HTML] Engineering customized nanovaccines for enhanced cancer immunotherapy
J Guo, C Liu, Z Qi, T Qiu, J Zhang, H Yang - Bioactive Materials, 2024 - Elsevier
Nanovaccines have gathered significant attention for their potential to elicit tumor-specific
immunological responses. Despite notable progress in tumor immunotherapy, nanovaccines …
immunological responses. Despite notable progress in tumor immunotherapy, nanovaccines …
cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice
Increasing preclinical and clinical results have demonstrated that mRNA vaccines efficiently
prevent infectious diseases and are safe in animal models and humans. In this study, we …
prevent infectious diseases and are safe in animal models and humans. In this study, we …
Pathophysiological roles and applications of glycosphingolipids in the diagnosis and treatment of cancer diseases
X Jin, GY Yang - Progress in Lipid Research, 2023 - Elsevier
Glycosphingolipids (GSLs) are major amphiphilic glycolipids present on the surface of living
cell membranes. They have important biological functions, including maintaining plasma …
cell membranes. They have important biological functions, including maintaining plasma …