Curcumin formulations for better bioavailability: what we learned from clinical trials thus far?

M Hegde, S Girisa, B BharathwajChetty, R Vishwa… - ACS …, 2023 - ACS Publications
Curcumin has been credited with a wide spectrum of pharmacological properties for the
prevention and treatment of several chronic diseases such as arthritis, autoimmune …

Antioxidants maintain cellular redox homeostasis by elimination of reactive oxygen species

L He, T He, S Farrar, L Ji, T Liu, X Ma - Cellular Physiology and …, 2017 - karger.com
Reactive oxygen species (ROS) are produced by living cells as normal cellular metabolic
byproduct. Under excessive stress conditions, cells will produce numerous ROS, and the …

Applications of chitosan-based carrier as an encapsulating agent in food industry

G Maleki, EJ Woltering, MR Mozafari - Trends in Food Science & …, 2022 - Elsevier
Background Certain food bioactives and nutraceuticals need to be preserved from
environmental factors such as pH, light, oxygen, temperature, and enzymatic degradation …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Curcumin‐piperine co‐supplementation and human health: a comprehensive review of preclinical and clinical studies

H Heidari, M Bagherniya, M Majeed… - Phytotherapy …, 2023 - Wiley Online Library
Curcumin is extracted from the rhizomes Curcuma longa L. It is known for its anti‐
inflammatory and anti‐oxidant activities. Despite its safety and potential for use against …

Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy

K Mortezaee, E Salehi… - Journal of cellular …, 2019 - Wiley Online Library
Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is
one of the most important challenges in medicine. Improving therapeutic outcomes from …

Immune modulation by curcumin: The role of interleukin-10

H Mollazadeh, AFG Cicero, CN Blesso… - Critical reviews in …, 2019 - Taylor & Francis
Cytokines are small secreted proteins released by different types of cells with specific effects
on cellular signaling and communication via binding to their receptors on the cell surface. IL …

Experimental and clinical reports on anti‐inflammatory, antioxidant, and immunomodulatory effects of Curcuma longa and curcumin, an updated and comprehensive …

A Memarzia, MR Khazdair, S Behrouz… - …, 2021 - Wiley Online Library
Curcuma longa (C. longa) or turmeric is a plant with a long history of use in traditional
medicine, especially for treating inflammatory conditions C. longa and its main constituent …

Mechanisms underlying the pathophysiology of type 2 diabetes: From risk factors to oxidative stress, metabolic dysfunction, and hyperglycemia

JEBF Lima, NCS Moreira, ET Sakamoto-Hojo - Mutation Research/Genetic …, 2022 - Elsevier
Abstract Type 2 diabetes (T2D) is a complex multifactorial disease that emerges from the
combination of genetic and environmental factors, and obesity, lifestyle, and aging are the …

A review of the molecular mechanisms of hyperglycemia‐induced free radical generation leading to oxidative stress

H Yaribeygi, SL Atkin… - Journal of cellular …, 2019 - Wiley Online Library
The prevalence of diabetes is growing worldwide with an increasing morbidity and mortality
associated with the development of diabetes complications. Free radical production is a …