Microbial production of advanced biofuels

J Keasling, H Garcia Martin, TS Lee… - Nature Reviews …, 2021 - nature.com
Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …

Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently

A Currin, N Swainston, PJ Day, DB Kell - Chemical Society Reviews, 2015 - pubs.rsc.org
The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …

Subcellular compartmentalization in the biosynthesis and engineering of plant natural produces

L Yao, X Wu, X Jiang, M Shan, Z Zhang, Y Li… - Biotechnology …, 2023 - Elsevier
Plant natural products (PNPs) are specialized metabolites with diverse bioactivities. They
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …

[PDF][PDF] Engineering tolerance to industrially relevant stress factors in yeast cell factories

Q Deparis, A Claes, MR Foulquié-Moreno… - FEMS yeast …, 2017 - academic.oup.com
The main focus in development of yeast cell factories has generally been on establishing
optimal activity of heterologous pathways and further metabolic engineering of the host …

Strategies for enhancing microbial tolerance to inhibitors for biofuel production: a review

S Wang, X Sun, Q Yuan - Bioresource Technology, 2018 - Elsevier
Using lignocellulosic biomass for the production of renewable biofuel provides a sustainable
and promising solution to the crisis of energy and environment. However, the processes of …

Metabolic engineering of microorganisms for biofuel production

P Majidian, M Tabatabaei, M Zeinolabedini… - … and Sustainable Energy …, 2018 - Elsevier
Microorganisms directly and indirectly contribute to production of diverse biofuels.
Heterotrophic microorganisms are being used for commercial production of biofuels such as …

Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis

DB Kell, N Swainston, P Pir, SG Oliver - Trends in biotechnology, 2015 - cell.com
Because they mainly do not involve chemical changes, membrane transporters have been a
Cinderella subject in the biotechnology of small molecule production, but this is a serious …

Enhancing biofuels production by engineering the actin cytoskeleton in Saccharomyces cerevisiae

H Liu, P Zhou, M Qi, L Guo, C Gao, G Hu… - Nature …, 2022 - nature.com
Saccharomyces cerevisiae is widely employed as a cell factory for the production of biofuels.
However, product toxicity has hindered improvements in biofuel production. Here, we …

Engineering the oleaginous yeast Yarrowia lipolytica to produce limonene from waste cooking oil

Y Pang, Y Zhao, S Li, Y Zhao, J Li, Z Hu… - Biotechnology for …, 2019 - Springer
Background Limonene is an important biologically active natural product widely used in the
food, cosmetic, nutraceutical and pharmaceutical industries. However, the low abundance of …

Engineering endogenous ABC transporter with improving ATP supply and membrane flexibility enhances the secretion of β-carotene in Saccharomyces cerevisiae

X Bu, JY Lin, J Cheng, D Yang, CQ Duan… - Biotechnology for …, 2020 - Springer
Background Product toxicity is one of the bottlenecks for microbial production of biofuels,
and transporter-mediated biofuel secretion offers a promising strategy to solve this problem …