Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update
JM Kyriakis, J Avruch - Physiological reviews, 2012 - journals.physiology.org
The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …
were first elucidated in 1994, and by 2001, substantial progress had been made in …
Rho GTPases: biochemistry and biology
AB Jaffe, A Hall - Annu. Rev. Cell Dev. Biol., 2005 - annualreviews.org
Approximately one percent of the human genome encodes proteins that either regulate or
are regulated by direct interaction with members of the Rho family of small GTPases …
are regulated by direct interaction with members of the Rho family of small GTPases …
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
JM Kyriakis, J Avruch - Physiological reviews, 2001 - journals.physiology.org
The molecular details of mammalian stress-activated signal transduction pathways have
only begun to be dissected. This, despite the fact that the impact of these pathways on the …
only begun to be dissected. This, despite the fact that the impact of these pathways on the …
Rho GTPases and their effector proteins
AL Bishop, A Hall - Biochemical Journal, 2000 - portlandpress.com
Rho GTPases are molecular switches that regulate many essential cellular processes,
including actin dynamics, gene transcription, cell-cycle progression and cell adhesion …
including actin dynamics, gene transcription, cell-cycle progression and cell adhesion …
A comprehensive pathway map of epidermal growth factor receptor signaling
K Oda, Y Matsuoka, A Funahashi… - Molecular systems …, 2005 - embopress.org
The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important
pathways that regulate growth, survival, proliferation, and differentiation in mammalian cells …
pathways that regulate growth, survival, proliferation, and differentiation in mammalian cells …
Rho GTPases and signaling networks
L Van Aelst, C D'Souza-Schorey - Genes & development, 1997 - genesdev.cshlp.org
The Rho GTPases form a subgroup of the Ras superfamily of 20-to 30-kD GTP-binding
proteins that have been shown to regulate a wide spectrum of cellular functions. These …
proteins that have been shown to regulate a wide spectrum of cellular functions. These …
Signal transduction through MAP kinase cascades
TS Lewis, PS Shapiro, NG Ahn - Advances in cancer research, 1998 - Elsevier
Publisher Summary The chapter introduces the mitogen-activated protein (MAP) kinase
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of …
(MAPK) module. The identification of MAP kinase pathways exemplifies the power of …
[HTML][HTML] Regulation of actin cytoskeleton dynamics in cells
SH Lee, R Dominguez - Molecules and cells, 2010 - Elsevier
The dynamic remolding of the actin cytoskeleton is a critical part of most cellular activities,
and malfunction of cytoskeletal proteins results in various human diseases. The transition …
and malfunction of cytoskeletal proteins results in various human diseases. The transition …
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
G Joberty, C Petersen, L Gao, IG Macara - Nature cell biology, 2000 - nature.com
Abstract PAR (partitioning-defective) proteins, which were first identified in the nematode
Caenorhabditis elegans, are essential for asymmetric cell division and polarized growth …
Caenorhabditis elegans, are essential for asymmetric cell division and polarized growth …
Cell polarization and cytokinesis in budding yeast
E Bi, HO Park - Genetics, 2012 - academic.oup.com
Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …