Prevalence and incidence of Huntington's disease: an updated systematic review and meta‐analysis
A Medina, Y Mahjoub, L Shaver… - Movement …, 2022 - Wiley Online Library
The incidence and prevalence of Huntington's disease (HD) based on a systematic review
and meta‐analysis of 20 studies published from 1985 to 2010 was estimated at 0.38 per …
and meta‐analysis of 20 studies published from 1985 to 2010 was estimated at 0.38 per …
An update on the neurological short tandem repeat expansion disorders and the emergence of long-read sequencing diagnostics
SR Chintalaphani, SS Pineda, IW Deveson… - Acta Neuropathologica …, 2021 - Springer
Background Short tandem repeat (STR) expansion disorders are an important cause of
human neurological disease. They have an established role in more than 40 different …
human neurological disease. They have an established role in more than 40 different …
Characterization and visualization of tandem repeats at genome scale
Tandem repeat (TR) variation is associated with gene expression changes and numerous
rare monogenic diseases. Although long-read sequencing provides accurate full-length …
rare monogenic diseases. Although long-read sequencing provides accurate full-length …
The role of brain derived neurotrophic factor in central nervous system
Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …
A review on accelerometry-based gait analysis and emerging clinical applications
Gait analysis continues to be an important technique for many clinical applications to
diagnose and monitor certain diseases. Many mental and physical abnormalities cause …
diagnose and monitor certain diseases. Many mental and physical abnormalities cause …
Stem cell-derived exosomes: a new strategy of neurodegenerative disease treatment
N Fayazi, M Sheykhhasan, S Soleimani Asl… - Molecular …, 2021 - Springer
Short-term symptomatic treatment and dose-dependent side effects of pharmacological
treatment for neurodegenerative diseases have forced the medical community to seek an …
treatment for neurodegenerative diseases have forced the medical community to seek an …
A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical …
M Ciosi, A Maxwell, SA Cumming, DJH Moss… - …, 2019 - thelancet.com
Background Huntington disease (HD) is caused by an unstable CAG/CAA repeat expansion
encoding a toxic polyglutamine tract. Here, we tested the hypotheses that HD outcomes are …
encoding a toxic polyglutamine tract. Here, we tested the hypotheses that HD outcomes are …
[图书][B] The language game: How improvisation created language and changed the world
MH Christiansen, N Chater - 2022 - books.google.com
'Marvellously clear... playfully persuasive'Richard Dawkins' Full of Fascinating details. A
delight to read.'Tim Harford'Highly original and convincing... a delight to read!'-Daniel …
delight to read.'Tim Harford'Highly original and convincing... a delight to read!'-Daniel …
The role of vitamins in neurodegenerative disease: An update
SN Rai, P Singh, HWM Steinbusch, E Vamanu… - Biomedicines, 2021 - mdpi.com
Acquiring the recommended daily allowance of vitamins is crucial for maintaining
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …
Stem cell transplantation therapy and neurological disorders: current status and future perspectives
Simple Summary This review highlights the scope of available treatment options for
neurological diseases, especially stem cell transplantation therapy, which provides new …
neurological diseases, especially stem cell transplantation therapy, which provides new …