Role of metabolic endotoxemia in systemic inflammation and potential interventions

S Mohammad, C Thiemermann - Frontiers in immunology, 2021 - frontiersin.org
Diet-induced metabolic endotoxemia is an important factor in the development of many
chronic diseases in animals and man. The gut epithelium is an efficient barrier that prevents …

The ecology and evolution of pangenomes

MA Brockhurst, E Harrison, JPJ Hall, T Richards… - Current Biology, 2019 - cell.com
Since the first genome-scale comparisons, it has been evident that the genomes of many
species are unbound by strict vertical descent: Large differences in gene content can occur …

A neutrophil response linked to tumor control in immunotherapy

J Gungabeesoon, NA Gort-Freitas, M Kiss, E Bolli… - Cell, 2023 - cell.com
Neutrophils accumulate in solid tumors, and their abundance correlates with poor prognosis.
Neutrophils are not homogeneous, however, and could play different roles in cancer …

Endosymbiotic theories for eukaryote origin

WF Martin, S Garg, V Zimorski - … Transactions of the …, 2015 - royalsocietypublishing.org
For over 100 years, endosymbiotic theories have figured in thoughts about the differences
between prokaryotic and eukaryotic cells. More than 20 different versions of endosymbiotic …

Complex archaea that bridge the gap between prokaryotes and eukaryotes

A Spang, JH Saw, SL Jørgensen… - Nature, 2015 - nature.com
The origin of the eukaryotic cell remains one of the most contentious puzzles in modern
biology. Recent studies have provided support for the emergence of the eukaryotic host cell …

GET_HOMOLOGUES, a versatile software package for scalable and robust microbial pangenome analysis

B Contreras-Moreira, P Vinuesa - Applied and environmental …, 2013 - Am Soc Microbiol
ABSTRACT GET_HOMOLOGUES is an open-source software package that builds on
popular orthology-calling approaches making highly customizable and detailed pangenome …

A genomic update on clostridial phylogeny: G ram‐negative spore formers and other misplaced clostridia

N Yutin, MY Galperin - Environmental microbiology, 2013 - Wiley Online Library
The class C lostridia in the phylum F irmicutes (formerly low‐G+ CG ram‐positive bacteria)
includes diverse bacteria of medical, environmental and biotechnological importance. The S …

Biochemistry and evolution of anaerobic energy metabolism in eukaryotes

M Müller, M Mentel, JJ van Hellemond… - Microbiology and …, 2012 - Am Soc Microbiol
Major insights into the phylogenetic distribution, biochemistry, and evolutionary significance
of organelles involved in ATP synthesis (energy metabolism) in eukaryotes that thrive in …

An archaeal origin of eukaryotes supports only two primary domains of life

TA Williams, PG Foster, CJ Cox, TM Embley - Nature, 2013 - nature.com
The discovery of the Archaea and the proposal of the three-domains 'universal'tree, based
on ribosomal RNA and core genes mainly involved in protein translation, catalysed new …

Proteinortho: Detection of (Co-)orthologs in large-scale analysis

M Lechner, S Findeiß, L Steiner, M Marz, PF Stadler… - BMC …, 2011 - Springer
Background Orthology analysis is an important part of data analysis in many areas of
bioinformatics such as comparative genomics and molecular phylogenetics. The ever …