Association of MMP-2 and MMP-9 polymorphisms with diabetes and pathogenesis of diabetic complications

B Gajewska, M Śliwińska-Mossoń - International Journal of Molecular …, 2022 - mdpi.com
Type 2 diabetes mellitus (T2D) affects millions of people around the world, and its
complications have serious health consequences. In addition to external factors, the causes …

Классификация, регуляция активности, генетический полиморфизм матриксных металлопротеиназ в норме и при патологии

АС Шадрина, ЯЗ Плиева, ДН Кушлинский… - Альманах …, 2017 - cyberleninka.ru
Матриксные металлопротеиназы (ММП)–семейство цинксодержащих эндопептидаз,
катализирующих реакции деградации компонентов внеклеточного матрикса. У …

MMPs and TIMPs levels are correlated with anthropometric parameters, blood pressure, and endothelial function in obesity

S Boumiza, K Chahed, Z Tabka, MP Jacob, X Norel… - Scientific reports, 2021 - nature.com
The association between matrix metalloproteinases (MMPs), tissue inhibitor of
metalloproteinases (TIMPs) and obesity as well as obesity-related disease including …

Matrix metalloproteinase (MMP)-2-1306 C> T gene polymorphism affects circulating levels of MMP-2 in Egyptian asthmatic patients

MA Elkady, GM Abd-Allah, AS Doghish, AA Yousef… - Gene Reports, 2016 - Elsevier
Asthma is a common chronic inflammatory ailment affects the respiratory system leading to
bronchial hyper-reactivity. Both genetic and environmental factors play a principal role in …

Classification, regulation of activity, and genetic polymorphism of matrix metalloproteinases in health and disease

AS Shadrina, YZ Plieva, DN Kushlinskiy… - Almanac of clinical …, 2017 - almclinmed.ru
Matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases that
catalyze the degradation reactions of the extracellular matrix components. In humans, 23 …

[HTML][HTML] 儿童青少年主要健康问题“共病-共因-共防” 机制建立与探索

宋逸, 张秀红, 马军 - 中国学校卫生, 2023 - cjsh.org.cn
近年来, 近视, 肥胖, 心理健康等儿童青少年健康问题已引起全社会的关注, 成为重要的公共卫生
问题. 中国儿童青少年主要健康问题的单病流行负担不容乐观, 且同时面临着较高的共病患病率 …

The role of molecular and hormonal factors in obesity and the effects of physical activity in children

J Aragón-Vela, J Alcalá-Bejarano Carrillo… - International Journal of …, 2022 - mdpi.com
Obesity and overweight are defined as abnormal fat accumulations. Adipose tissue consists
of more than merely adipocytes; each adipocyte is closely coupled with the extracellular …

Crosstalk between obesity and MMP-9 in cardiac remodelling–a cross-sectional study in apparent treatment-resistant hypertension

AMV Ritter, AP de Faria, N Barbaro, AR Sabbatini… - Blood …, 2017 - Taylor & Francis
The balance between matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP)
plays a key role in the development of hypertension and obesity. We aimed to evaluate the …

Matrix metalloproteinases 2 and 9 polymorphism in patients with myeloproliferative diseases: a STROBE-compliant observational study

S Maral, M Acar, OS Balcik, E Uctepe, OF Hatipoglu… - Medicine, 2015 - journals.lww.com
Chronic myeloproliferative disorders such as polycythemia vera (PV), essential
thrombocytosis (ET), and idiopathic myelofibrosis arise from clonal proliferation of neoplastic …

Increased activity of MMP‐2 in hypertensive obese children is associated with hypoadiponectinemia

VA Belo, R Lacchini, JA Miranda, CMM Lanna… - …, 2015 - Wiley Online Library
Objective To compare the circulating levels of MMP‐2 and TIMP‐2 and the MMP‐2/TIMP‐2
ratio in control, obese, and obese hypertensive children and adolescents and to assess …