Autism spectrum disorders (ASDs) comprise a heterogeneous group of pathological
conditions, mainly of genetic origin, characterized by stereotyped behavior, marked …

This review aims to summarize the latest evidence about the role of innate and adaptive
immunity in Amyotrophic Lateral Sclerosis (ALS). ALS is a devastating neurodegenerative …

Sporadic amyotrophic lateral sclerosis (sALS) is a progressive neuroinflammatory disease of
spinal cord motor neurons of unclear etiology. Blood from 38 patients with sALS, 28 aged …

Protons are the most ubiquitous and very potent modulators of the biological systems.
Hydrogen ions are known to modulate GABAA receptors (GABAARs), but the mechanism …

Astrocytes releasing glucose‐and/or glycogen‐derived lactate and glutamine play a crucial
role in shaping neuronal function and plasticity. Little is known, however, how metabolic …

The microtubule binding protein gephyrin plays a prominent role in establishing and
maintaining a high concentration of inhibitory glycine receptors juxtaposed to presynaptic …

The cell adhesion molecule Neuroligin2 (NL2) is localized selectively at GABAergic
synapses, where it interacts with the scaffolding protein gephyrin in the post-synaptic …

Recent studies have emphasized that nonequilibrium conditions of postsynaptic GABAA
receptor (GABAAR) activation is a key factor in shaping the time course of IPSCs (;). Such …

The time course of GABA-evoked currents is the main source of information on the
GABAAreceptor gating. Since the kinetics of these currents depends on the transitions …

Memantine, a clinically used N-methyl-d-aspartate (NMDA)-receptor antagonist, has been
shown to prevent apoptotic neuronal damage connected with the over-activity of NMDA …