Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-
established causal role in several cancers. Recent studies have provided compelling …

Epidemiological studies have provided compelling evidence that multiple sclerosis (MS) is a
rare complication of infection with the Epstein–Barr virus (EBV), a herpesvirus that infects …

Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

Multiple sclerosis is a chronic inflammatory disease of the CNS that results from the interplay
between heritable and environmental factors. Mounting evidence from different fields of …

Epstein-Barr virus (EBV) is usually acquired silently early in life and carried thereafter as an
asymptomatic infection of the B lymphoid system. However, many circumstances disturb the …

Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within
families and the sharp decline in risk with increasing genetic distance, it cannot fully explain …

Multiple sclerosis (MS) is a chronic inflammatory, likely autoimmune disease of the central
nervous system with a combination of genetic and environmental risk factors, among which …

Although strong genetic determinants of multiple sclerosis (MS) exist, the findings of
migration studies support a role for environmental factors in this disease. Through rigorous …

Biomarkers can be thought of as multifaceted indicators of healthy status or of pathological
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …