KaKs_Calculator 3.0: calculating selective pressure on coding and non-coding sequences

Z Zhang - Genomics, Proteomics and Bioinformatics, 2022 - academic.oup.com
Abstract KaKs_Calculator 3.0 is an updated toolkit that is capable of calculating selective
pressure on both coding and non-coding sequences. Similar to the nonsynonymous …

LncBook 2.0: integrating human long non-coding RNAs with multi-omics annotations

Z Li, L Liu, C Feng, Y Qin, J Xiao… - Nucleic Acids …, 2023 - academic.oup.com
LncBook, a comprehensive resource of human long non-coding RNAs (lncRNAs), has been
used in a wide range of lncRNA studies across various biological contexts. Here, we present …

Discovering microproteins: making the most of ribosome profiling data

S Chothani, L Ho, S Schafer, O Rackham - RNA biology, 2023 - Taylor & Francis
Building a reference set of protein-coding open reading frames (ORFs) has revolutionized
biological process discovery and understanding. Traditionally, gene models have been …

[HTML][HTML] What can ribo-seq, immunopeptidomics, and proteomics tell us about the noncanonical proteome?

JR Prensner, JG Abelin, LW Kok, KR Clauser… - Molecular & Cellular …, 2023 - ASBMB
Abstract Ribosome profiling (Ribo-Seq) has proven transformative for our understanding of
the human genome and proteome by illuminating thousands of noncanonical sites of …

[HTML][HTML] Small open Reading frame-encoded Micro-peptides: an emerging protein world

X Dong, K Zhang, C Xun, T Chu, S Liang… - International Journal of …, 2023 - mdpi.com
Small open reading frames (sORFs) are often overlooked features in genomes. In the past,
they were labeled as noncoding or “transcriptional noise”. However, accumulating evidence …

NPInter v5. 0: ncRNA interaction database in a new era

Y Zheng, H Luo, X Teng, X Hao, X Yan… - Nucleic acids …, 2023 - academic.oup.com
Noncoding RNAs (ncRNAs) play key regulatory roles in biological processes by interacting
with other biomolecules. With the development of high-throughput sequencing and …

OpenProt 2.0 builds a path to the functional characterization of alternative proteins

S Leblanc, F Yala, N Provencher, JF Lucier… - Nucleic Acids …, 2024 - academic.oup.com
The OpenProt proteogenomic resource (https://www. openprot. org/) provides users with a
complete and freely accessible set of non-canonical or alternative open reading frames …

EVLncRNAs 3.0: an updated comprehensive database for manually curated functional long non-coding RNAs validated by low-throughput experiments

B Zhou, B Ji, C Shen, X Zhang, X Yu… - Nucleic Acids …, 2024 - academic.oup.com
Long noncoding RNAs (lncRNAs) have emerged as crucial regulators across diverse
biological processes and diseases. While high-throughput sequencing has enabled lncRNA …

Ribo-uORF: a comprehensive data resource of upstream open reading frames (uORFs) based on ribosome profiling

Q Liu, X Peng, M Shen, Q Qian, J Xing, C Li… - Nucleic Acids …, 2023 - academic.oup.com
Upstream open reading frames (uORFs) are typically defined as translation sites located
within the 5′ untranslated region upstream of the main protein coding sequence (CDS) of …

The new uORFdb: integrating literature, sequence, and variation data in a central hub for uORF research

F Manske, L Ogoniak, L Jürgens… - Nucleic Acids …, 2023 - academic.oup.com
Upstream open reading frames (uORFs) are initiated by AUG or near-cognate start codons
and have been identified in the transcript leader sequences of the majority of eukaryotic …