Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
Targeting Sirt1, AMPK, Nrf2, CK2, and soluble guanylate cyclase with nutraceuticals: a practical strategy for preserving bone mass
MF McCarty, L Lewis Lujan, S Iloki Assanga - International Journal of …, 2022 - mdpi.com
There is a vast pre-clinical literature suggesting that certain nutraceuticals have the potential
to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid …
to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid …
[HTML][HTML] Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype.
Radiotherapy is an effective option for the treatment of TNBC; however, acquired …
Radiotherapy is an effective option for the treatment of TNBC; however, acquired …
Severe COVID-19 is characterised by perturbations in plasma amines correlated with immune response markers, and linked to inflammation and oxidative stress
The COVID-19 pandemic raised a need to characterise the biochemical response to SARS-
CoV-2 infection and find biological markers to identify therapeutic targets. In support of these …
CoV-2 infection and find biological markers to identify therapeutic targets. In support of these …
Hydrogen sulfide in bone tissue regeneration and repair: state of the art and new perspectives
The importance of hydrogen sulfide (H2S) in the regulation of multiple physiological
functions has been clearly recognized in the over 20 years since it was first identified as a …
functions has been clearly recognized in the over 20 years since it was first identified as a …
Therapeutic potential of endogenous hydrogen sulfide inhibition in breast cancer
M Li, Y Liu, Y Deng, L Pan, H Fu, X Han… - Oncology …, 2021 - spandidos-publications.com
Abstract Hydrogen sulfide (H 2 S), the third gas signal molecule, is associated with the
modulation of various physiological and pathological processes. Recent studies have …
modulation of various physiological and pathological processes. Recent studies have …
Gasotransmitters in pregnancy: from conception to uterine involution
Gasotransmitters are endogenous small gaseous messengers exemplified by nitric ox ide
(NO), carbon monoxide (CO), and hydrogen sulfide (H2S or sulfide). Gasotransmitters are …
(NO), carbon monoxide (CO), and hydrogen sulfide (H2S or sulfide). Gasotransmitters are …
Optimization of small molecule degraders and antagonists for targeting estrogen receptor based on breast cancer: current status and future
J Yao, Y Tao, Z Hu, J Li, Z Xue, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
The estrogen receptor (ER) is a classical receptor protein that plays a crucial role in
mediating multiple signaling pathways in various target organs. It has been shown that ER …
mediating multiple signaling pathways in various target organs. It has been shown that ER …
[HTML][HTML] Hypoxia preconditioning of human MSCs: a direct evidence of HIF-1α and collagen type XV correlation
E Lambertini, L Penolazzi, M Angelozzi… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Mesenchymal stromal cells (MSCs) hold considerable promise in bone
tissue engineering, but their poor survival and potency when in vivo implanted limits their …
tissue engineering, but their poor survival and potency when in vivo implanted limits their …
Estrogen regulates local cysteine metabolism in mouse myometrium
Sulfur amino acid metabolism influences reproductive physiology, and transsulfuration in
particular may be critical for normal cellular function. The sex hormone estrogen (E 2) …
particular may be critical for normal cellular function. The sex hormone estrogen (E 2) …