Following research obtained from the previous SARS and MERS outbreaks, we've gained
knowledge about the mechanisms of bioactive plant ingredients against the attachment and …

Abstract Background The Notch signaling pathway is a cell signaling system that is
conserved in a variety of eukaryotes. Overall, Notch receptors and their ligands are single …

Background Z-DNA binding protein 1 (ZBP1) is a vital innate immune sensor that regulates
inflammation during pathogen invasion. ZBP1 may contribute to pyroptosis, apoptosis and …

Introduction The aim of this study was to investigate the role of the proinflammatory axis TNF-
α–TNFR1 in experimentally induced periapical inflammation and bone resorption in mice …

The development, establishment and repair of apical periodontitis (AP) is dependent of
several factors, which include host susceptibility, microbial infection, immune response …

Apical periodontitis (AP) is featured by a persistent inflammatory response and alveolar
bone resorption initiated by microorganisms, posing risks to both dental and systemic health …

Objectives Notch signaling pathway, known to influence bone resorption in several oral
diseases, has not been analyzed in peri‐implantitis yet. Therefore, the aims of the present …

The Notch pathway is an evolutionarily preserved signaling pathway involved in a variety of
vital cell functions. Additionally, it is one of the key regulators of inflammation, and controls …

Introduction This study was intended to evaluate the expression of inflammatory cytokines
commonly secreted by CD4+ T cells (IL-2, IL-5, IL-17, TGF-β, TNF-α, and IFN-γ) in apical …

Aim To assess the periapical alveolar bone pattern and the serum levels of proinflammatory
cytokines, biochemical markers and metabolites in rats subjected to chronic alcohol and …