Red blood cells (RBC) are the most abundant cell in the human body, with a central role in
oxygen transport and its delivery to tissues. However, omics technologies recently revealed …

Mature red blood cells (RBCs) lack mitochondria and thus exclusively rely on glycolysis to
generate adenosine triphosphate (ATP) during aging in vivo or storage in blood banks …

Different mesoporous nanomaterials (MSNs) are constantly being developed for a range of
therapeutic purposes, but they invariably interact with blood components and may cause …

The development of red blood cell (RBC) storage lesion during hypothermic storage has
long posed challenges for blood transfusion efficacy. These alterations are primarily driven …

Background The Red blood cell (RBC) storage lesion results in decreased circulation and
function of transfused RBCs. Elevated oxidant stress and impaired energy metabolism are a …

Eukaryotic cells are defined as cells containing distinct nuclei and other membranous
organelles. However, red blood cells (RBCs) lack a nucleus and organelles—perhaps to …

Favism uniquely arises from a genetic defect of the Glucose-6 Phosphate Dehydrogenase
(G6PD) enzyme and results in a severe reduction of erythrocytes'(RBCs) reducing power …

Gain-of-function mutations in PIEZO1 cause dehydrated hereditary stomatocytosis (DHS) or
hereditary xerocytosis, an autosomal dominant hemolytic anemia characterized by high …

Genetic characteristics of blood donors may impact the storability of blood products. Despite
higher basal stress, red blood cells (RBCs) from eligible donors that are heterozygous for …

Background Ion and metal homeostasis are critical to red blood cell physiology and
Inductively Coupled Plasma (ICP) is a decades old approach to pursue elemental analysis …