Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

One of the challenges in cancer chemotherapy is the low target to non-target ratio of
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …

Triple-negative breast cancer (TNBC) is more aggressive and difficult to treat using
conventional bulk chemotherapy that is often associated with increased toxicity and side …

Simple Summary Breast cancer is one of the leading causes of death among women
worldwide. Breast cancer may be provoked due to several physical, chemical and …

Cancer is one of the leading causes of death worldwide due to high heterogeneity. Although
chemotherapy remains the mainstay of cancer therapy, non-selective toxicity and drug …

Hollow mesoporous silica nanoparticles (HMSNs) served as nanocarriers for transporting
doxorubicin hydrochloride (DOX) and indocyanine green (ICG) and were incorporated into a …

Multidrug resistance (MDR) is the main challenge faced by cancer chemotherapy. Drug-
conjugate offers a promising strategy for breast cancer therapy. In this regard, we developed …

Emerging multifunctional nanoparticulate formulations take advantage of nano-meter scale
size and surface chemistry to work as a therapeutic delivery agent and a diagnostic tool for …

Breast cancer therapeutic intervention continues to be ambiguous owing to the lack of
strategies for targeted transport and receptor-mediated uptake of drugs by cancer cells. In …

Breast cancer treatment is hampered by drug resistance which leads to recurrence and
metastasis. Alteration of specific gene expression such as ERCC1 evidently acquires drug …