Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Recent advances in active targeting of nanomaterials for anticancer drug delivery
One of the challenges in cancer chemotherapy is the low target to non-target ratio of
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
therapeutic agents which incur severe adverse effect on the healthy tissues. In this regard …
Drug-encapsulated blend of PLGA-PEG microspheres: in vitro and in vivo study of the effects of localized/targeted drug delivery on the treatment of triple-negative …
Triple-negative breast cancer (TNBC) is more aggressive and difficult to treat using
conventional bulk chemotherapy that is often associated with increased toxicity and side …
conventional bulk chemotherapy that is often associated with increased toxicity and side …
Plant Derived Bioactive Compounds, Their Anti-Cancer Effects and In Silico Approaches as an Alternative Target Treatment Strategy for Breast Cancer: An Updated …
V Shrihastini, P Muthuramalingam, S Adarshan… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is one of the leading causes of death among women
worldwide. Breast cancer may be provoked due to several physical, chemical and …
worldwide. Breast cancer may be provoked due to several physical, chemical and …
Learn from antibody–drug conjugates: consideration in the future construction of peptide-drug conjugates for cancer therapy
M Wu, W Huang, N Yang, Y Liu - Experimental Hematology & Oncology, 2022 - Springer
Cancer is one of the leading causes of death worldwide due to high heterogeneity. Although
chemotherapy remains the mainstay of cancer therapy, non-selective toxicity and drug …
chemotherapy remains the mainstay of cancer therapy, non-selective toxicity and drug …
Hyaluronic acid-functionalized hollow mesoporous silica nanoparticles as pH-sensitive nanocarriers for cancer chemo-photodynamic therapy
Y Zhou, C Chang, Z Liu, Q Zhao, Q Xu, C Li, Y Chen… - Langmuir, 2021 - ACS Publications
Hollow mesoporous silica nanoparticles (HMSNs) served as nanocarriers for transporting
doxorubicin hydrochloride (DOX) and indocyanine green (ICG) and were incorporated into a …
doxorubicin hydrochloride (DOX) and indocyanine green (ICG) and were incorporated into a …
Stimuli-responsive, dual-function prodrug encapsulated in hyaluronic acid micelles to overcome doxorubicin resistance
Multidrug resistance (MDR) is the main challenge faced by cancer chemotherapy. Drug-
conjugate offers a promising strategy for breast cancer therapy. In this regard, we developed …
conjugate offers a promising strategy for breast cancer therapy. In this regard, we developed …
LHRH conjugated gold nanoparticles assisted efficient ovarian cancer targeting evaluated via spectral photon-counting CT imaging: a proof-of-concept research
D Kumar, M Moghiseh, K Chitcholtan… - Journal of Materials …, 2023 - pubs.rsc.org
Emerging multifunctional nanoparticulate formulations take advantage of nano-meter scale
size and surface chemistry to work as a therapeutic delivery agent and a diagnostic tool for …
size and surface chemistry to work as a therapeutic delivery agent and a diagnostic tool for …
[HTML][HTML] Receptor-mediated targeted delivery of surface-ModifiedNanomedicine in breast cancer: Recent update and challenges
Breast cancer therapeutic intervention continues to be ambiguous owing to the lack of
strategies for targeted transport and receptor-mediated uptake of drugs by cancer cells. In …
strategies for targeted transport and receptor-mediated uptake of drugs by cancer cells. In …
Fabrication and evaluation of a dual-targeting nanoparticle mediated CRISPR/Cas9 delivery to combat drug resistance in breast cancer cells
N Tavazohi, M Mirian, J Varshosaz… - Journal of Drug Delivery …, 2023 - Elsevier
Breast cancer treatment is hampered by drug resistance which leads to recurrence and
metastasis. Alteration of specific gene expression such as ERCC1 evidently acquires drug …
metastasis. Alteration of specific gene expression such as ERCC1 evidently acquires drug …