[HTML][HTML] Pulmonary vascular remodeling in pulmonary hypertension

Z Jia, S Wang, H Yan, Y Cao, X Zhang, L Wang… - Journal of Personalized …, 2023 - mdpi.com
Pulmonary vascular remodeling is the critical structural alteration and pathological feature in
pulmonary hypertension (PH) and involves changes in the intima, media and adventitia …

[HTML][HTML] Interleukin-6 and pulmonary hypertension: from physiopathology to therapy

WJ Xu, Q Wu, WN He, S Wang, YL Zhao… - Frontiers in …, 2023 - frontiersin.org
Pulmonary hypertension (PH) is a progressive, pulmonary vascular disease with high
morbidity and mortality. Unfortunately, the pathogenesis of PH is complex and remains …

The MALAT1-H19/miR-19b-3p axis can be a fingerprint for diabetic neuropathy

M Rajabinejad, G Asadi, S Ranjbar, FR Varmaziar… - Immunology letters, 2022 - Elsevier
Background: Diabetic neuropathy (DN) is one of the most common microvascular
complications of diabetes that is attributed to impaired immune regulation. In this study, we …

Downregulation of lncRNA NEAT1 Ameliorates LPS-Induced Inflammatory Responses by Promoting Macrophage M2 Polarization via miR-125a-5p/TRAF6/TAK1 Axis

W Wang, ZH Guo - Inflammation, 2020 - Springer
The lncRNA nuclear enriched abundant transcript 1 (NEAT1) promotes sepsis-inflammatory
responses and acute kidney injury (AKI), but little known about the underlying mechanisms …

[HTML][HTML] miR-29a-3p/THBS2 axis regulates PAH-induced cardiac fibrosis

CH Hsu, IF Liu, HF Kuo, CY Li, WS Lian… - International journal of …, 2021 - mdpi.com
Pulmonary artery hypertension (PAH) pathology involves extracellular matrix (ECM)
remodeling in cardiac tissues, thus promoting cardiac fibrosis progression. miR-29a-3p …

An evolutionary machine learning for pulmonary hypertension animal model from arterial blood gas analysis

B Shi, T Zhou, S Lv, M Wang, S Chen… - Computers in Biology …, 2022 - Elsevier
Pulmonary hypertension (PH) is a rare and fatal condition that leads to right heart failure and
death. The pathophysiology of PH and potential therapeutic approaches are yet unknown …

[HTML][HTML] Epigenetic regulation of programmed cell death in hypoxia-induced pulmonary arterial hypertension

Y Jiang, S Song, J Liu, L Zhang, X Guo, J Lu… - Frontiers in …, 2023 - frontiersin.org
Pulmonary arterial hypertension (PAH) is a severe progressive disease that may cause early
right ventricular failure and eventual cardiac failure. The pathogenesis of PAH involves …

[HTML][HTML] MiR-125a-5p promotes osteoclastogenesis by targeting TNFRSF1B

L Sun, JX Lian, S Meng - Cellular & Molecular Biology Letters, 2019 - Springer
Aim To investigate the dysregulation of microRNAs (miRNAs) during the differentiation of
osteoclasts and the precise roles of miR-125a-5p in the differentiation of osteoclasts …

[HTML][HTML] Circ-Ntrk2 acts as a miR-296-5p sponge to activate the TGF-β1/p38 MAPK pathway and promote pulmonary hypertension and vascular remodelling

L Su, X Li, X Mao, T Xu, Y Zhang, S Li, X Zhu… - Respiratory …, 2023 - Springer
Abstract Background Circular RNAs (circRNAs), a novel class of non-coding RNAs, play an
important regulatory role in pulmonary arterial hypertension (PAH); however, the specific …

MicroRNA-125a suppresses intestinal mucosal inflammation through targeting ETS-1 in patients with inflammatory bowel diseases

Y Ge, M Sun, W Wu, C Ma, C Zhang, C He, J Li… - Journal of …, 2019 - Elsevier
Abstract MicroRNA (miR)-125a is highly expressed in T cells and regulates the functions of
Treg through the IL-6-STAT3 signaling pathway. However, the role of miR-125a in regulating …