The role of hydrophobic amino acids in the structure and function of the rhodopsin family of G protein-coupled receptors

G Caltabiano, A Gonzalez, A Cordomí, M Campillo… - Methods in …, 2013 - Elsevier
Recent advances in crystallization methods have permitted to resolve the molecular
structure of several members of the rhodopsin family of G protein-coupled receptors …

Functional elements of the gastric inhibitory polypeptide receptor: Comparison between secretin-and rhodopsin-like G protein-coupled receptors

A Cordomi, S Ismail, MT Matsoukas, C Escrieut… - Biochemical …, 2015 - Elsevier
Innovative crystallographic techniques have resulted in an exponential growth in the number
of solved G-protein coupled receptor (GPCR) structures and a better understanding of the …

Understanding Corticotropin releasing factor receptor (CRFR) activation using structural models

A Cordomi, G Liapakis… - Current Molecular …, 2017 - ingentaconnect.com
The corticotropin-releasing factor type 1 and 2 receptors (CRF1R and CRF2R) belong to the
secretin-like family, also known as class B1, of G protein-coupled receptors (GPCRs) …

The hydrophobic amino acid cluster at the cytoplasmic end of transmembrane helix III modulates the coupling of the ß1-adrenergic receptor to Gs

H Hajjhussein, LA Gardner, N Fujii… - Journal of Receptors …, 2013 - Taylor & Francis
A cluster of hydrophobic amino acids at the cytoplasmic end of trans-membranal helix III (TM-
III) is a common feature among class-A of G protein-coupled receptors (GPCR). We …

Sirt7 acts as a novel regulator of chromatin dynamics through modulation of the Sirt1/Suv39H1 axis: Possible role in cancer

P Kumari - 2020 - jlupub.ub.uni-giessen.de
Sirtuins build a family of NAD+-dependent histone and protein deacetylases that are
involved in a variety of cellular processes including proliferation, metabolism, genomic …

Characterization of amino acid changes in visual pigment evolution and interaction with associated proteins

MA Fernández Sampedro - 2018 - upcommons.upc.edu
Visual opsins are G protein-coupled receptors that function as light photoreceptors in the
vertebrate retina. Rhodopsin is the visual pigment located in the rod photoreceptor cells …

[引用][C] 一个先天性静止性夜盲症家系致病基因的突变分析

王凤羽, 王艳丽, 杨洋, 李聪敏, 张涛, 常明秀, 朱运良 - 中华医学遗传学杂志, 2012