Alternative splicing (AS) serves as a pivotal mechanism in transcriptional regulation,
engendering transcript diversity, and modifications in protein structure and functionality …

RNA-binding proteins (RBPs) are evolutionarily conserved across most forms of life, with an
estimated 1,500 RBPs in humans. Traditionally associated with post-transcriptional gene …

Cisplatin resistance is a major cause of therapeutic failure in patients with high-grade serous
ovarian cancer (HGSOC). Long noncoding RNAs (lncRNAs) have emerged as key …

Cervical cancer (CC) is the most common gynecologic malignancy, which seriously
threatens the health of women. Lipid metabolism is necessary for tumor proliferation and …

SARS-CoV-2 is a betacoronavirus with single-stranded positive-sense RNA, which is a
serious global threat to human health. Understanding the molecular mechanism of viral …

Although the majority of RNAs are retained in the nucleus, their significance is often
overlooked. However, it is now becoming clear that nuclear RNA forms a dynamic structure …

Alternative Polyadenylation (APA) is an emerging mechanism for dynamic changes in gene
expression. Previously, we described widespread APA occurrence in introns during the DNA …

Rationale: Tumor cells remodel transcriptome to construct an ecosystem with stemness
features, which maintains tumor growth and highly malignant characteristics. However, the …

Glioblastoma (GBM) is the most lethal and common primary tumor of central nervous system
with a poor prognosis. Glioma stem cells (GSCs) are particularly significant in GBM …

RNA binding proteins (RBPs) are increasingly recognized as potential factors influencing
the advancement, prognostication, and immune response in various solid tumors …