Exercise for osteoarthritis: a literature review of pathology and mechanism

H Kong, XQ Wang, XA Zhang - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Osteoarthritis (OA) has a very high incidence worldwide and has become a very common
joint disease in the elderly. Currently, the treatment methods for OA include surgery, drug …

Role of physical exercise and nutraceuticals in modulating molecular pathways of osteoarthritis

A de Sire, N Marotta, C Marinaro, C Curci… - International Journal of …, 2021 - mdpi.com
Osteoarthritis (OA) is a painful and disabling disease that affects millions of patients. Its
etiology is largely unknown, but it is most likely multifactorial. OA pathogenesis involves the …

Polysaccharide from Angelica sinensis protects chondrocytes from H2O2-induced apoptosis through its antioxidant effects in vitro

C Zhuang, NW Xu, GM Gao, S Ni, KS Miao… - International journal of …, 2016 - Elsevier
This study aimed to explore the protective effects of Angelica sinensis polysaccharide (ASP)
on rat chondrocyte injury induced by hydrogen peroxide (H 2 O 2). Rat chondrocytes were …

[HTML][HTML] IL-10 reduces apoptosis and extracellular matrix degradation after injurious compression of mature articular cartilage

P Behrendt, A Preusse-Prange, T Klüter… - Osteoarthritis and …, 2016 - Elsevier
Objective The aim of this study was to examine whether anti-inflammatory interleukin-10 (IL-
10) exerts chondroprotective effects in an in vitro model of a single mechanical injury of …

IL-10 and TGF-β: Roles in chondroprotective effects of Glucosamine in experimental Osteoarthritis?

NE Waly, A Refaiy, NM Aborehab - Pathophysiology, 2017 - Elsevier
Objective Osteoarthritis (OA) is a complex disease of the whole joint. Glucosamine (GlcN)
treatment may have a chondroprotective effect on OA. We investigated the mechanism of …

Long noncoding RNA MALAT‐1 inhibits apoptosis and matrix metabolism disorder in interleukin‐1β‐induced inflammation in articular chondrocytes via the JNK …

GC Gao, XG Cheng, QQ Wei, WC Chen… - Journal of Cellular …, 2019 - Wiley Online Library
Proinflammatory cytokine such as interleukin (IL)‐1β causes inflammation of articular
cartilage. In this current study, we explored the chondroprotective effects of long noncoding …

Interleukin-10 and collagen type II immunoexpression are modulated by photobiomodulation associated to aerobic and aquatic exercises in an experimental model of …

L Assis, C Tim, A Magri, KR Fernandes… - Lasers in medical …, 2018 - Springer
The aim of this study was to compare the effects of photobiomodulation (PBM) associated
with an aerobic and an aquatic exercise training on the degenerative process related to …

Physical exercise and low-level laser therapy on the nociception and leukocyte migration of Wistar rats submitted to a model of rheumatoid arthritis

M Neves, ACB Retameiro, ALF Tavares… - Lasers in medical …, 2020 - Springer
Rheumatoid arthritis denotes hyperplasia and intense inflammatory process. Treatment
involves exercise protocols and use of resources such as low-level laser therapy (LLLT) to …

The interrelation of osteoarthritis and diabetes mellitus: considering the potential role of interleukin-10 and in vitro models for further analysis

S Schwarz, I Mrosewski, S Silawal… - Inflammation …, 2018 - Springer
Introduction Today, not only the existence of an interrelation between obesity/adipositas and
osteoarthritis (OA) but also the association of OA and diabetes mellitus (DM) are widely …

Animal Models of Osteoarthritis: Updated Models and Outcome Measures 2016–2023

JH Chapman, D Ghosh, S Attari, CC Ude… - Regenerative …, 2024 - Springer
Purpose Osteoarthritis (OA) is a global musculoskeletal disorder that affects primarily the
knee and hip joints without any FDA-approved disease-modifying therapies. Animal models …