Transfection is a powerful analytical tool enabling studies of gene products and functions in
eukaryotic cells. Successful delivery of genetic material into cells depends on DNA quantity …

Cationic liposomes (CLs) are effective carriers of a variety of therapeutics. Their applications
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …

Over the past few decades, gene therapy has gained immense importance in medical
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …

Liposomes are nanocarriers comprised of lipid bilayers encapsulating an aqueous core. The
ability of liposomes to encapsulate a wide variety of diagnostic and therapeutic agents has …

Cancer is a highly complex disease to understand, because it entails multiple cellular
physiological systems. The most common cancer treatments are restricted to chemotherapy …

Recent mechanistic studies have attempted to deepen our understanding of the process by
which liposome-mediated delivery of genetic material occurs. Understanding the …

Lipid-based carriers represent the most widely used alternative to viral vectors for gene
expression and gene silencing purposes. This class of non-viral vectors is particularly …

DNA is proving to be a powerful scaffold to construct molecularly precise designer DNA
devices. Recent trends reveal their ever-increasing deployment within living systems as …

Breast cancer is the most frequently diagnosed cancer among women. Breast cancer is also
the key reason for worldwide cancer-related deaths among women. The application of small …

Cationic lipids have become known as one of the most versatile tools for the delivery of
DNA, RNA and many other therapeutic molecules, and are especially attractive because …