Lipids are a complex and diverse group of molecules with crucial roles in many
physiological processes, as well as in the onset, progression, and maintenance of cancers …

Mitochondria regulate hepatic lipid metabolism and oxidative stress. Ultrastructural
mitochondrial lesions, altered mitochondrial dynamics, decreased activity of respiratory …

This review discusses the current state of the viral metabolism field and gaps in knowledge
that will be important for future studies to investigate. We discuss metabolic rewiring caused …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Almost all patients with hepatocellular carcinoma (HCC), a major type of primary liver
cancer, also have liver cirrhosis, the severity of which hampers effective treatment for HCC …

Background & Aims Cancer-associated fibroblasts (CAFs) play a key role in the cancer
process, but the research progress is hampered by the paucity of preclinical models that are …

Primary liver cancers, including hepatocellular carcinoma and intrahepatic
cholangiocarcinoma, are leading causes of cancer-related death worldwide. Recent large …

Dengue virus is responsible for the highest rates of disease and mortality among the
members of the Flavivirus genus. Dengue epidemics are still occurring around the world …

The pathogenesis of hepatocellular carcinoma (HCC) is poorly understood, but recent
advances in genomics have increased our understanding of the mechanisms by which …

Hepatocellular carcinoma (HCC) is the commonest primary malignant cancer of the liver in
the world. Given that the burden of chronic liver disease is expected to rise owing to …