Consequences of paternal nutrition on offspring health and disease

P Dimofski, D Meyre, N Dreumont, B Leininger-Muller - Nutrients, 2021 - mdpi.com
It is well established that the maternal diet during the periconceptional period affects the
progeny's health. A growing body of evidence suggests that the paternal diet also influences …

Neuroactive steroids, neurosteroidogenesis and sex

S Giatti, LM Garcia-Segura, GE Barreto… - Progress in …, 2019 - Elsevier
The nervous system is a target and a source of steroids. Neuroactive steroids are steroids
that target neurons and glial cells. They include hormonal steroids originated in the …

Sex differences in steroid levels and steroidogenesis in the nervous system: Physiopathological role

S Giatti, S Diviccaro, MM Serafini, D Caruso… - Frontiers in …, 2020 - Elsevier
The nervous system, in addition to be a target for steroid hormones, is the source of a variety
of neuroactive steroids, which are synthesized and metabolized by neurons and glial cells …

Interactions between nutrients in the maternal diet and the implications for the long-term health of the offspring

WD Rees - Proceedings of the Nutrition Society, 2019 - cambridge.org
Nutritional science has traditionally used the reductionist approach to understand the roles
of individual nutrients in growth and development. The macronutrient dense but …

Periconceptional folate deficiency leads to autism-like traits in Wistar rat offspring

S Degroote, D Hunting, L Takser - Neurotoxicology and teratology, 2018 - Elsevier
Background Folates in their role as key one carbon donors, are essential for two major
pathways: the synthesis of DNA and RNA precursors and DNA methylation. A growing body …

Pituitary adenylate cyclase-activating polypeptide excites proopiomelanocortin neurons: implications for the regulation of energy homeostasis

R Chang, J Hernandez, C Gastelum, K Guadagno… - …, 2020 - karger.com
Objective: We examined whether pituitary adenylate cyclase-activating polypeptide
(PACAP) excites proopiomelanocortin (POMC) neurons via PAC1 receptor mediation and …

Beneficial effects of omega‐3 fatty acids and vitamin B12 supplementation on brain docosahexaenoic acid, brain derived neurotrophic factor, and cognitive …

RS Rathod, AA Khaire, AA Kale, SR Joshi - Biofactors, 2015 - Wiley Online Library
In vegetarian population, vitamin B12 deficiency coexists with suboptimal levels of omega‐3
fatty acids. Studies indicate a need for supplementation/fortification of vitamin B12 and …

Cross‐Talk between miRNAs from the Dlk1‐Dio3 Locus and Histone Methylation to Protect Male Cerebellum from Methyl Donor Deficiency

J Willekens, P Mosca, N Burt‐Oberecken… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Disruption of the one carbon metabolism during development, ie, following a
gestational vitamin B9 and B12 deficiencies, is involved in birth defects and brain …

Molecular mechanisms of synergistic analgesic and neuroprotective action of B group vitamins according to the results of proteomic analysis

OA Gromova, IY Torshin - Neurology, Neuropsychiatry …, 2023 - nnp.ima-press.net
We present the results of a systemic biological analysis of human proteome proteins,
biological functions of which are somehow related to the metabolism of B group vitamins …

Cerebellum transcriptome of mice bred for high voluntary activity offers insights into locomotor control and reward-dependent behaviors

K Caetano-Anollés, JS Rhodes, T Garland Jr… - PloS one, 2016 - journals.plos.org
The role of the cerebellum in motivation and addictive behaviors is less understood than that
in control and coordination of movements. High running can be a self-rewarding behavior …