Because bone-associated diseases are increasing, a variety of tissue engineering
approaches with bone regeneration purposes have been proposed over the last years …

Bone regenerative medicine is a clinical approach combining live osteoblast progenitors,
such as mesenchymal stromal cells (MSCs), with a biocompatible scaffold that can integrate …

Abstract Background: Three-dimensional (3D) printed bone tissue engineering scaffolds
have been widely used in research and clinical applications. β-TCP is a biomaterial …

A preclinical evaluation using a regenerative medicine methodology comprising an
additively manufactured medical-grade ε-polycaprolactone β-tricalcium phosphate (mPCL …

Iron overload has been reported to contribute to bone marrow mesenchymal stem cells
(BMSCs) damage, but the precise mechanism still remains elusive. Icariin, a major bioactive …

The aim of the study is to determine the effectiveness of stem cells in scaffolds in the
treatment of bone deficits, in regard of bone regeneration, safety, rehabilitation and quality of …

Abstract Background Wharton's Jelly (WJ) Mesenchymal Stromal Cells (MSC) have
emerged as an attractive allogeneic therapy for a number of indications, except for bone …

Mesenchymal stem/stromal cells (MSCs) have various properties that make them promising
candidates for stem cell-based therapies in clinical settings. These include self-renewal …

The role played by mesenchymal stem cells (MSCs) in contributing to adult tissue
homeostasis and damage repair thanks to their differentiation capabilities has raised a great …

Abstract Background Mesenchymal stem cells (MSCs) have alluring interest for clinical use
in orthopaedics based on their therapeutic potential through directed pluripotent …