Evolution of Drug-Resistant Mycobacterium tuberculosis Strains and Their Adaptation to the Human Lung Environment
A Allué-Guardia, JI García, JB Torrelles - Frontiers in Microbiology, 2021 - frontiersin.org
In the last two decades, multi (MDR), extensively (XDR), extremely (XXDR) and total (TDR)
drug-resistant Mycobacterium tuberculosis (M. tb) strains have emerged as a threat to public …
drug-resistant Mycobacterium tuberculosis (M. tb) strains have emerged as a threat to public …
Drug-resistant strains of Mycobacterium tuberculosis: cell envelope profiles and interactions with the host
A Schami, MN Islam, JT Belisle… - Frontiers in Cellular and …, 2023 - frontiersin.org
In the past few decades, drug-resistant (DR) strains of Mycobacterium tuberculosis (M. tb),
the causative agent of tuberculosis (TB), have become increasingly prevalent and pose a …
the causative agent of tuberculosis (TB), have become increasingly prevalent and pose a …
Immunometabolism during Mycobacterium tuberculosis infection
NC Howard, SA Khader - Trends in microbiology, 2020 - cell.com
Over a quarter of the world's population is infected with Mycobacterium tuberculosis (Mtb),
the causative agent of tuberculosis (TB). Approximately 3.4% of new and 18% of recurrent …
the causative agent of tuberculosis (TB). Approximately 3.4% of new and 18% of recurrent …
Biomarker discovery for tuberculosis using metabolomics
Y Yu, XX Jiang, JC Li - Frontiers in molecular biosciences, 2023 - frontiersin.org
Tuberculosis (TB) is the leading cause of death among infectious diseases, and the ratio of
cases in which its pathogen Mycobacterium tuberculosis (Mtb) is drug resistant has been …
cases in which its pathogen Mycobacterium tuberculosis (Mtb) is drug resistant has been …
Drivers and sites of diversity in the DNA adenine methylomes of 93 Mycobacterium tuberculosis complex clinical isolates
SJ Modlin, D Conkle-Gutierrez, C Kim, SN Mitchell… - Elife, 2020 - elifesciences.org
This study assembles DNA adenine methylomes for 93 Mycobacterium tuberculosis
complex (MTBC) isolates from seven lineages paired with fully-annotated, finished, de novo …
complex (MTBC) isolates from seven lineages paired with fully-annotated, finished, de novo …
Cell surface biosynthesis and remodeling pathways in mycobacteria reveal new drug targets
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains the
leading cause of death from an infectious bacterium and is responsible for 1.8 million deaths …
leading cause of death from an infectious bacterium and is responsible for 1.8 million deaths …
Elucidating the antimycobacterial mechanism of action of ciprofloxacin using metabolomics
In the interest of developing more effective and safer anti-tuberculosis drugs, we used a
GCxGC-TOF-MS metabolomics research approach to investigate and compare the …
GCxGC-TOF-MS metabolomics research approach to investigate and compare the …
The Regulation of ManLAM-Related Gene Expression in Mycobacterium tuberculosis with Different Drug Resistance Profiles Following Isoniazid Treatment
M Yimcharoen, S Saikaew… - Infection and drug …, 2022 - Taylor & Francis
Introduction Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) remains a
global health concern because of the development of drug resistance. The adaptability of …
global health concern because of the development of drug resistance. The adaptability of …
Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane‐anchoring properties
Tuberculosis (TB) is one of the leading causes of human death caused by Mycobacterium
tuberculosis (Mtb). Mtb can enter into a long‐lasting persistence where it can utilize fatty …
tuberculosis (Mtb). Mtb can enter into a long‐lasting persistence where it can utilize fatty …
Lineage-specific differences in lipid metabolism and its impact on clinical strains of Mycobacterium tuberculosis
K Moopanar, NE Mvubu - Microbial pathogenesis, 2020 - Elsevier
Mycobacterium tuberculosis (M. tb) is the causative agent of TB and its incidences has been
on the rise since 1993. Lipid metabolism is an imperative metabolic process, which grants …
on the rise since 1993. Lipid metabolism is an imperative metabolic process, which grants …