Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

For many years, transcription factor Sp1 was viewed as a basal transcription factor and
relegated to a role in the regulation of so‐called housekeeping genes. Identification of Sp1's …

Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

Gastric cancer remains highly prevalent and accounts for a notable proportion of global
cancer mortality. This cancer is also associated with poor survival rates. Understanding the …

Abstract Loss of cadherin 1 (CDH1; also known as epithelial cadherin (E-cadherin)) is used
for the diagnosis and prognosis of epithelial cancers. However, it should not be ignored that …

Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

Endocytosis entails selective packaging of cell-surface proteins, such as receptors for
cytokines and adhesion components, in cytoplasmic vesicles (endosomes). The series of …

Abstract Development, regeneration and cancer involve drastic transitions in tissue
morphology. In analogy with the behaviour of inert fluids, some of these transitions have …

E‐cadherin protein (CDH1 gene) integrity is fundamental to the process of epithelial
polarization and differentiation. Deregulation of the E‐cadherin function plays a crucial role …

E‐cadherin (epithelial‐cadherin), encoded by the CDH1 gene, is a transmembrane
glycoprotein playing a crucial role in maintaining cell‐cell adhesion. E‐cadherin has been …