Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …

Among the various bacterial infections, tuberculosis continues to hold center stage. Its
causative agent, Mycobacterium tuberculosis, possesses robust defense mechanisms …

The integral membrane protein ATG9A plays a key role in autophagy. It displays a broad
intracellular distribution and is present in numerous compartments, including the plasma …

Cancer cells display altered cellular lipid metabolism, including disruption in endogenous
lipid synthesis, storage, and exogenous uptake for membrane biogenesis and functions …

Mycobacterium tuberculosis (Mtb) is a very successful pathogen, strictly adapted to humans
and the cause of tuberculosis. Its success is associated with its ability to inhibit host cell …

The clinically important Mycobacterium tuberculosis (M. tb) and related mycobacterial
pathogens use various virulence mechanisms to survive and cause disease in their hosts …

Autophagy is an important innate immune defense mechanism that controls Mycobacterium
tuberculosis (Mtb) growth inside macrophages. Autophagy machinery targets Mtb-containing …

Mycobacterium tuberculosis (Mtb) synthesizes a variety of atypical lipids that are exposed at
the cell surface and help the bacterium infect macrophages and escape elimination by the …

Mycobacterial disease is an immense burden worldwide. This disease group includes
tuberculosis, leprosy (Hansen's disease), Buruli Ulcer, and non-tuberculous mycobacterial …

Intracellular pathogens commonly manipulate the host lysosomal system for their survival.
However, whether this pathogen-induced alteration affects the organization and functioning …