Ten years of anti-vascular endothelial growth factor therapy

N Ferrara, AP Adamis - Nature reviews Drug discovery, 2016 - nature.com
The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …

[HTML][HTML] Ocular drug delivery to the retina: current innovations and future perspectives

HM Kim, SJ Woo - Pharmaceutics, 2021 - mdpi.com
Treatment options for retinal diseases, such as neovascular age-related macular
degeneration, diabetic retinopathy, and retinal vascular disorders, have markedly expanded …

[HTML][HTML] Expert opinion on management of intraocular inflammation, retinal vasculitis, and vascular occlusion after brolucizumab treatment

CR Baumal, B Bodaghi, M Singer, DJ Tanzer… - Ophthalmology …, 2021 - Elsevier
Purpose Recent reports have described a spectrum of uncommon findings of intraocular
inflammation (IOI), retinal vasculitis and/or retinal vascular occlusion in patients with …

Anti‐vascular endothelial growth factor for neovascular age‐related macular degeneration

SD Solomon, K Lindsley, SS Vedula… - Cochrane Database …, 2014 - cochranelibrary.com
Background Age‐related macular degeneration (AMD) is the most common cause of
uncorrectable severe vision loss in people aged 55 years and older in the developed world …

Ranibizumab for neovascular age-related macular degeneration

PJ Rosenfeld, DM Brown, JS Heier… - … England Journal of …, 2006 - Mass Medical Soc
Background Ranibizumab—a recombinant, humanized, monoclonal antibody Fab that
neutralizes all active forms of vascular endothelial growth factor A—has been evaluated for …

[HTML][HTML] Diabetic retinopathy and VEGF

N Gupta, S Mansoor, A Sharma, A Sapkal… - The open …, 2013 - ncbi.nlm.nih.gov
Diabetic retinopathy remains the leading vascular-associated cause of blindness throughout
the world. Its treatment requires a multidisciplinary interventional approach at both systemic …

[PDF][PDF] Age-related macular degeneration (AMD): pathogenesis and therapy

JZ Nowak - Pharmacological reports, 2006 - Citeseer
Age-related macular degeneration (AMD) is a disease leading to severe visual loss and
legal blindness in the elderly population. Its pathogenesis, likely multifactorial, involving a …

Meta-analysis of endophthalmitis after intravitreal injection of anti–vascular endothelial growth factor agents: causative organisms and possible prevention strategies

CA Mccannel - Retina, 2011 - journals.lww.com
Purpose: To report the rates of endophthalmitis and the spectrum of causative organisms
after intravitreal injection of anti-vascular endothelial growth factor agents and possible …

An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration

AE Fung, GA Lalwani, PJ Rosenfeld, SR Dubovy… - American journal of …, 2007 - Elsevier
PURPOSE: To evaluate an optical coherence tomography (OCT)-guided, variable-dosing
regimen with intravitreal ranibizumab for the treatment of patients with neovascular age …

Randomized, double-masked, sham-controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER Study year 1

CD Regillo, DM Brown, P Abraham, H Yue… - American journal of …, 2008 - Elsevier
PURPOSE: To evaluate the efficacy and safety of ranibizumab administered monthly for
three months and then quarterly in patients with subfoveal choroidal neovascularization …